Spinal Cord Diseases, Spinal Cord Injuries
Conditions
Brief summary
So far, therapies have limited success in functional recovery in adults with chronic SCI. By introducing remote cognitive multisensory rehabilitation (CMR), which has shown significant functional improvements due to neurological recovery when delivered in-person, transformative results that (i) provide a potentially effective new therapy within the healthcare system, accessible to more patients, and (ii) demonstrate brain function changes alongside improved function in chronic SCI are anticipated. The results will inform and justify a large scale federally funded clinical trial.
Interventions
BEHAVIORALRemote CMR
12 weeks of remote CMR is done 3x/week, 45 min/session.
BEHAVIORALRemote Exercise
12 weeks of remote exercise is done 3x/week, 45 min/session.
Sponsors
University of Minnesota
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* 18-75 years old, with an incomplete or complete SCI/D of ≥ 3months, medically stable. * be recruited from Hospitals within the Minnesota Regional Spinal Cord Injury Model System (MN Regional SCIMS), HealthPartners Neuroscience Center, Minneapolis VA Healthcare System, Duluth, and in the community.
Exclusion criteria
* adults with MRI contra-indications (stabilizing hardware is typically MRI safe); * adults with uncontrolled seizure disorder; * adults with cognitive impairment and/or communicative disability (e.g., due to brain injury) that prevent them from following directions or from learning; * adults with with ventilator dependency; * adults with other major medical complications * pregnant women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) Neurologic Exam | baseline | a clinical test originally designed to describe the extent and severity of a patient's SCI/D |
| the Neuromuscular Recovery Scale (NRS) | baseline | includes 11 items focused on the capacity of the trunk and lower extremity muscles to perform tasks such as sit, trunk extension, sit to stand, walking, and step retraining. The NRS provides a functional recovery measure that focuses on non-compensatory recovery. |
| The SCI-FI/AT | baseline | (32 items) reliably measures function in the domains of basic mobility, self-care, fine motor function, and ambulation. |
Countries
United States
Outcome results
None listed