Health Knowledge, Attitudes, Practice
Conditions
Brief summary
The proposed study aims to test the effects of supplementing healthy individuals (with low baseline vegetable consumption) with 5 servings of vegetables (80-120g per serving) per day for 4 weeks on blood lipids and other cardiometabolic outcomes. Previous studies indicate the potential to see significant effects in this population and within this amount of time. Importantly, the investigators will also be including a weekly cooking demonstration as part of the intervention, which provides an essential hands-on participatory component and allows participants to connect with one another in a group setting, which aids in acceptability and adherence to dietary interventions. The investigators hypothesize that 4 weeks of daily supplementation with 4-5 servings of vegetables will significantly improve LDL-C and other cardiometabolic outcomes in healthy adults.
Interventions
DIETARY_SUPPLEMENTVegetables
4-5 servings of vegetables daily, per USDA guidelines.
Sponsors
University of Arizona
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* 18-65 years of age * Consuming a typical American diet (i.e. not engaged in a structured diet) * Willing and able to eat vegetables provided (i.e. not allergic or adverse to vegetables provided).
Exclusion criteria
* Pregnant or lactating * Participants who currently eat 5+ servings/cups of vegetables per day (excluding tomato paste/sauce, and fried potatoes 'French fries') * Any condition that would interfere with the participant's data, at the study team's discretion.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| LDL-C/non-HDL-C | 4-6 weeks | — |
| Brachial and central blood pressure | 4-6 weeks | systolic and diastolic pressures |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Glucose | 4-6 weeks | Fasting blood glucose |
| Augmentation Index | 4-6 weeks | augmentation index corrected for heart rate augmentation index corrected for heart rate |
| Other lipids and lipoproteins | 4-6 weeks | HDL-C, total cholesterol, and triglycerides |
Countries
United States
Outcome results
None listed