Skip to content

Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care: CRT

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05869552
Enrollment
1485
Registered
2023-05-22
Start date
2023-07-13
Completion date
2027-03-31
Last updated
2025-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Suicidal Ideation, Suicide

Keywords

depression, Self-Injurious Behavior, sexual and gender minority youth

Brief summary

The overall aim of this study is to reduce suicide among sexual and gender diverse youth ages 18-24 years old. This study will compare the effectiveness of two brief suicide prevention interventions that have been adapted for use with this population to use in primary care via telehealth and will recruit youth from primary care clinics in multiple metropolitan areas. The primary study outcome is suicidal ideation. Each clinic will be randomly assigned to deliver one of the two study interventions.

Interventions

OTHERSTAT-PC

STAT-PC is an adapted version of Suicidal Teens Accessing Treatment after an ED Visit (STAT-ED). It is a brief intervention based on motivational interviewing (MI) that focuses on mental health care seeking behavior, problem-solving, and referrals plus brief case management. The intervention will consist of an initial session with the youth focusing on accessing mental health care plus case management calls. The interventionist will also be available to assist with referrals for connection to other services later during the study period as needed for up to three months. The intervention may include contact with the youth's mental health provider to make sure linkages are made.

OTHERYST-III

YST-III is an adapted version of Youth-Nominated Support Team for Suicidal Adolescents (YST-II). The intervention is a brief intervention originally developed for youth who have been psychiatrically hospitalized due to a suicide attempt or suicidal ideation (SI). Participants will nominate supportive adults (age 18 and older) from their lives who agree to provide ongoing contact and support for up to 3 months. YST-III will include an introductory session with the youth who will nominate their support persons plus referrals for mental health services. The support persons will receive training and support on how to best support their youth partner and then ongoing calls to support them in working with their youth partner for up to 3 months.

Sponsors

Patient-Centered Outcomes Research Institute
CollaboratorOTHER
Elizabeth Arnold
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 24 Years
Healthy volunteers
No

Inclusion criteria

* be aged 18-24 at the time of enrollment * not have received mental health services in the past 90 days, excluding medication and case management * English-speaking * screen positive for suicide risk

Exclusion criteria

* are actively suicidal * have a developmental disability that would preclude them from participating in the study intervention * who are impaired due to psychosis, mania, or substance use that would prevent them from providing consent. * Participants will also be excluded at YST-III sites if they are unable to identify a minimum of one support person to participate in the intervention with them

Design outcomes

Primary

MeasureTime frameDescription
Change in suicidal ideation as measured by the Adult Suicidal Ideation Questionnaire (ASIQ)baseline and months 1, 3, 6ASIQ is a 25-item, self-report assessment of suicidal thoughts designed specifically for adult populations. Possible scores range from 1 (Not at All) to 6 (Extreme), with lower scores indicating less severe suicidal ideation (better outcome).

Secondary

MeasureTime frameDescription
Change in number of suicide attemptsbaseline and months 1, 3, 6measured by the number of suicide attempts using the Columbia-Suicide Severity Rating Scale (CSSRS)
Deaths by suicidebaseline to 6 monthsThe data on any reported deaths due to suicide during the study period will be collected.
Change in number of mental healthcare service utilization as measured by Emergency Department Screen for Teens at Risk for Suicide (ED-STARS) mental health service utilization check listbaseline and months 1, 3, 6ED-STARS mental health service utilization check list will be used to assess the number of different types of mental health services that participants receive
Change in social support as measured by the Multidimensional Scale of Perceived Social Support (MSPSS)baseline and months 1, 3, 612-item measure with three subscales that assesses family, friend, and significant other support. Response categories are on a 7-point Likert-scale from 1=very strongly disagree to 7=very strongly agree. The overall score will be used to assess change. The 12-item MSPSS scale has a mean continuous score ranging from 1-84. Higher scores indicate greater perceived social support (better outcome).
Change in internalized stigma as measured by Internalized Transphobia Scale (ITS)-adaptedbaseline and months 1, 3, 6an adapted version of the Internalized Transphobia Scale (ITS). The measure consists of 22 questions. Possible score ranges from 1-4 with lower scores indicating less internalized stigma (better outcome)
Change in depressive symptoms as measured by Center for Epidemiologic Studies Depression Scale-Revised CESD-Rbaseline and months 1, 3, 6CESD-R is a 20-item measure of depression that assesses the duration symptoms across a period of two weeks. Possible scores range from 0-60, with lower scores indicating less depressive symptoms (better outcome).

Countries

United States

Contacts

Primary ContactElizabeth Arnold, PhD
Liz.Arnold@uky.edu859-562-3751

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026