The Effects Of Low Intensity Training With Blood Flow Restriction In Rheumatoid Arthritis Patients

The Effects Of Low Intensity Training With Blood Flow Restriction In The Lower And Upper Limbs On Muscle Strength, Muscle Mass, Biochemical Parameters And Markers Of Systemic Inflammation In Rheumatoid Arthritis Patients: A Randomized Clinical Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05869370

Acronym

TBFR

Enrollment

Registered

2023-05-22

Start date

2018-05-20

Completion date

2025-12-31

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid Arthritis

Keywords

Rheumatoid Arthritis, Kaatsu, Blood Flow Restriction Training

Brief summary

Rheumatoid arthritis (RA) patients showed systemic manifestations that may lead to a reduction in muscle strength, muscle mass and, consequently, to a reduction in physical function. On the other hand, high intensity resistance training (HIRT) are able to improve muscle strength and muscle mass in RA without affecting the disease course. However, due to the articular manifestations caused by this disease, these patients may present intolerance to HIRT. Thus, the low intensity resistance training with blood flow restriction (TBFR) may be a new training strategy for these populations. In this sense, the investigators speculate that TBFR could be beneficial in RA patients, as well as, HIRT.

Interventions

OTHERHigh intensity resistance training

Twelve weeks of resistance training twice a week.

OTHERLow intensity resistance training combined with blood flow restriction

Twelve weeks of resistance training with blood flow restriction twice a week.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

45 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Female; * Rheumatoid arthritis patients; * All individuals will undergo an ergospirometry to ensure cardiorespiratory conditions.

Exclusion criteria

* Fibromyalgia; * Cardiovascular disease;

Design outcomes

Primary

Measure	Time frame	Description
Muscle strength	Twelve weeks	1 maximum repetition test.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026