Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block

Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block Utilizing Continuous Reassessment Method for Arthroscopic Rotator Cuff Shoulder Surgery

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05868993

Enrollment

150

Registered

2023-05-22

Start date

2023-02-17

Completion date

2025-12-31

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Operative Pain

Keywords

brachial plexus block

Brief summary

Prospective, patient-blinded study utilizing a novel Continuous Reassessment Method that concomitantly considers both block success and block side effects (lung dysfunction) for brachial plexus nerve blocks.

Detailed description

Success or failure of the brachial plexus block for any given volume will be determined by the verbal analogue pain scale score obtained 60 minutes after surgical end time. Volumes will be determined by continuous reassessment method.

Interventions

DRUGDose of 0.5% Ropivacaine

Dose varied by 5mL of 0.5% Ropivacaine

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Surgical candidate for Arthroscopic rotator cuff surgery * ASA I-III * BMI\<40 * Age \>18

Exclusion criteria

* Inability to give informed consent * Inability to complete consent process in English * allergy to ropivacaine * neuropathy * contraindications to peripheral nerve block per ASRA guidelines * chronic opioid use * infection at the injection/catheter site * limb restriction due to medical history * history of moderate - severe lung disease.

Design outcomes

Primary

Measure	Time frame	Description
Block Success	60min after surgery	Block success measured by pain (11-point VAS)
Lung Function	60 mins after surgery	Block success as measured by preservation of lung function (Vital Capacity in L)

Secondary

Measure	Time frame	Description
Diaphragm Excursion	60 minutes after surgery	Change in Movement of Diaphragm in cm
Vital Capacity	60 minutes after surgery	Change in Vital Capacity measured in L
Pulse Oximetry	60 minutes after surgery	Change in Pulse Oximetry Value
Side Effects	60 minutes after surgery	Rate of Dyspnea, Horner's, Hoarseness

Countries

United States

Contacts

Primary ContactDavid Auyong

anedba@vmmc.org206-223-6980

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026