Impatto Emodinamico Dell'Anestesia Subaracnoidea Titrata Versus Tecnica Single-shot Nei Pazienti Sottoposti ad Artroprotesi d'Anca. RCT

Impatto Emodinamico Dell'Anestesia Subaracnoidea Titrata Nel Confronto Con la Tecnica Tradizionale Single-shot Nei Pazienti Sottoposti ad Artroprotesi d'Anca. Trial Randomizzato Controllato

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05868642

Acronym

NINO

Enrollment

Registered

2023-05-22

Start date

2018-06-25

Completion date

2020-06-25

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia; Adverse Effect, Anesthesia, Local

Brief summary

Studying the hemodynamic effects of titrated subarachnoid anesthesia versus conventional single-shot subarachnoid anesthesia

Detailed description

This study aims to investigate whether a different hemodynamic effect is related to the injection o titrated local anesthetic for subarachnoid anesthesia versus the conventional single shot injection. The data to be recorded are blood pressure and pulse rate at different timing. As secondary outcomes the investigators will record the anesthetic level achieved using the Bromage score.

Interventions

PROCEDUREsubarachnoid block

subarachnoid block with levobupivacaine at different dosage for pation undergoing total hip arthroplasty

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

65 Years to 85 Years

Healthy volunteers

Inclusion criteria

* BMI 20-40 kg/m2 * ASA 1-3 * undergoing total hip arthroplasty * no controindications to subaracnhoid block * able to understand and sign a written informed consensus * METs \> o = 4

Exclusion criteria

* baseline SBP \< 100 mmHg

Design outcomes

Primary

Measure	Time frame	Description
SBP change	60 minute	SBP will be recorded at baseline and every 5 minutes after the subarachnoid block for 1 hour

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026