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Effect of Different Remineralization Gels

Effect of Different Remineralization Gels on the White Spot Lesions

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05868603
Enrollment
45
Registered
2023-05-22
Start date
2023-05-24
Completion date
2025-04-01
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

White Spot Lesion

Brief summary

The aim of the study is to treat white spot lesions that occur after orthodontic treatment. Different gels will be used for remineralization. The study will consist of 45 people between the ages of 15-18. 45 people will be divided into 3 groups.

Detailed description

Oral hygiene training will be given to each group and a toothpaste containing 1450 ppm fluoride will be given to brush their teeth twice a day. Essix appliance with reservoir will be made by taking impressions from 30 patients. Remineralization gel will be put into the Essix appliance for 5-7 minutes twice a day for one month.

Interventions

OTHERRemineralization gel

Remineralization gel

Sponsors

Marmara University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
15 Years to 18 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients aged 15-18 years, * Presence of white point lesions, * Volunteering to participate in the research.

Exclusion criteria

* Not having received orthodontic treatment, * Having a developmental anomaly affecting the enamel, * Being allergic to milk, * Having a syndrome affecting the oral cavity.

Design outcomes

Primary

MeasureTime frameDescription
Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP)4 weeksDecrease in laser fluorescence values with Diagnodent Pen as an indicator of remineralization

Secondary

MeasureTime frameDescription
Calcium glycerophosphate4 weeksDecrease in laser fluorescence values with Diagnodent Pen as an indicator of remineralization

Contacts

Primary ContactBetul Sen Yavuz, DDS
dt.betulsen@gmail.com+905399887646
Backup ContactDilanur Demiroglu, DDS
dilanurdemiroglu@gmail.com+905354911199

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026