Acute Kidney Injury, Diabetic Ketoacidosis
Conditions
Keywords
DKA AKI
Brief summary
Diabetic ketoacidosis (DKA), a severe complication of diabetes mellitus (DM), is the leading cause of hospitalization, morbidity and mortality in patients with DM (1). DKA is associated with hyperglycemic crises and featured by metabolic acidosis, the production of ketoacids, volume depletion, and electrolyte imbalance. Due to glucose-induced osmotic polyuria and even emesis, volume depletion is a major cause of acute kidney injury (AKI) in DKA patients (2).
Interventions
None listed
Sponsors
Study design
Eligibility
Inclusion criteria
* patients will be included in this study aged \>18 years old after diagnosis of AKI on top of Diabetic ketoacidosis at Sohag university hospital for all patients admitted during the period from May 2023 to May 2024
Exclusion criteria
* Chronic kidney disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| prognosis risk factors and outcomes of AKI in patients with DKA | 1 YEAR | complete resolution or progress to CKD or mortality and discover risk factors for AKI as uncontrolled diabetes infection or high uric acid uncontrolled hyperlipidemia |