Oxygen Deficiency, Survival, Prosthesis
Conditions
Keywords
acute respiratory distress syndrome, COVID-19, conscious, prone position, survival rate
Brief summary
The objective of our study is to evaluate the effectiveness of prone position in preventing intubation or death in spontaneously ventilated patients with COVID-19 with acute respiratory failure.
Detailed description
The COVID-19 pandemic has challenged the management of hypoxemic respiratory failure as limited ICU capacity is strained by a new high-mortality disease and large numbers of patients requiring prolonged periods of hospitalization, as well as respiratory support equipment such as ventilators and intensive care unit (ICU) beds. If early and prolonged prone positioning (DV) reduces mortality in invasively ventilated patients with acute respiratory distress syndrome (ARDS), its role in conscious patients (DV vigil) remains a subject of debate and research. This is a retrospective, monocentric, descriptive and analytical cohort conducted over a period of 22 months from March 2020 to December 2021 and involving 1069 patients hospitalized in the intensive care unit of the CHU Mohammed VI of Oujda for the management of acute respiratory failure caused by COVID-19.
Interventions
OTHERProne position
Each prone position session had a minimum duration of one hour and a maximum duration of 12 hours for a minimum of 3 hours per day.
Sponsors
Mohammed VI University Hospital
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* all patients (1069 patients) with ARDS due to SARS-cov2, confirmed by nasopharyngeal swab, who were hospitalized in the COVID-19 ICU from March 1, 2020 to December 31, 2021
Exclusion criteria
* Patients with negative CRP * Younger than 18 years of age * Patients who died or intubated on the day of admission * Patients presented a contraindication
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluate the effectiveness of awake prone position in preventing intubation or death in spontaneously ventilated patients with COVID-19 with acute respiratory failure. | 22 months | Evaluate the effectiveness of awake prone position in preventing intubation or death in spontaneously ventilated patients with COVID-19 with acute respiratory failure. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| length of stay in intensive care unit, length of time from hospitalization to death, length of time from hospitalization to intubation. | 22 months | length of stay in intensive care unit, length of time from hospitalization to death, length of time from hospitalization to intubation. |
Countries
Morocco
Outcome results
None listed