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Relationship of Addictions to Obesity, Physical Activity and Vascular Ageing in Young Adults

Relationship of Addictions to Obesity, Physical Activity and Vascular Ageing in Young Adults

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05866133
Enrollment
500
Registered
2023-05-19
Start date
2023-04-17
Completion date
2025-03-30
Last updated
2023-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug Addiction, Technology Addiction, Young Adult

Keywords

Lifestyles, Vascular ageing, Obesity

Brief summary

This is a cross-sectional observational study whose objective is to analyse the relationship between behavioural addictions and drug addictions with obesity, physical activity, sedentary lifestyle, arterial stiffness and vascular ageing in young adults, since many of the lifestyles of adulthood are established early in life, and it is easier to prevent them before they start than to achieve their abandonment once they are established as unhealthy lifestyles

Detailed description

Behavioural addictions. Brief Questionnaire of Pathological Gambling (CBJP), Lie/Bet scale, Compulsive Internet Use Scale (CIUS), Smartphone Dependence and Addiction Scale (EDAS-18), Questionnaire of Experiences Related to Video Games (CERV). Drug addictions: Alcohol, Smoking and Substance Involvement Screening Test (ASSIST V3.0), Drug Abuse Screening Test (DAST-20), Alcohol Use Disorders Identification Test (AUDIT) and Fagerström test. Obesity and body composition: Weight, height, waist circumference, hip circumference and Inbody 230®. Diet: Mediterranean Diet Adherence Questionnaire. Physical activity: International Physical Activity Questionnaire (IPAQ), Actigraph GTX3 accelerometer and Marshall questionnaire. Analysis of vascular structure and function and target organ lesions. Pulse wave analysis (PWA) and femoral carotid pulse wave velocity (VOPcf) (Sphygmocor System). Cardio Ankle Vascular Index (CAVI), ankle-ankle pulse wave (VOPbt) and ankle-ankle index (ABI) (Vasera VS-2000®). Retinal vascular injury (TOPCON TRC NW 200). Cardiac lesion (General electric 5000). Kidney Injury: analytical variables. Brain Injury: Montreal Cognitive Assessment (MoCA). Vascular ageing (VOPcf and VOPbt). Other variables. Basal glycaemia, HbA1c. TSH, lipid profile, creatinine and creatinine albumin index and Vit D. Measurement of blood pressure and drug consumption.

Interventions

None listed

Sponsors

Castilla-León Health Service
CollaboratorOTHER
Instituto de Investigación Biomédica de Salamanca
CollaboratorOTHER
Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 34 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients between 18 and 34 years of age who agree to participate in the study and do not meet any

Exclusion criteria

.

Design outcomes

Primary

MeasureTime frameDescription
Pulse wave velocity1 yearMeasurement by SphygmoCor (meters/seg)

Secondary

MeasureTime frameDescription
Accelerometer1 yearPhysical activity measurement using actigraph GTX3 accelerometer for 7 days (counts)
Body composition1 yearThe analysis of body composition shall be carried out with the impedance-meter Inbody 230® (kg).
International Physical Activity Questionnaire (IPAQ)1 yearPhysical activity measurement using the International Physical Activity Questionnaire (IPAQ) (min/day)
Cardio Ankle Vascular Index (CAVI)1 yearIt will be determined using the Vasera VS-2000® device (not units)
Pathological gambling1 yearBrief Questionnaire on Pathological Gambling (CBJP), with 4 dichotomous items (yes/no) referring to gambling habits, feelings of guilt, inability to give up gambling and use of household money for gambling. It is considered pathological from 2 points onwards. Also, Lie/Bet scale will also be used. It consists of two items, one of them referring to lying and the other to gambling, and will be considered problematic if both items are answered positively.
Internet use1 yearCompulsive Internet Use Scale (CIUS). It consists of 14 questions with a 5-point Likert scale for the answer. The cut-off point is 28.
Compulsive use of mobile phones1 yearSmartphone Dependence and Addiction Scale (EDAS-18). It consists of 18 questions with a 5-point Likert scale for the answer. Average scores: No dependence: ≤ 2.23; dependence: between 2.24 and 3.5; addiction: ≥ 3,6
Videogames use1 yearVideo Game Related Experiences Questionnaire (VREQ), with two dimensions: negative consequences and avoidance. It consists of 17 questions with a 4-point Likert scale for the answer. The cut-off point is 26 points.
Use or abuse of alcohol, tobacco and illegal drugs1 yearAlcohol, Smoking and Substance Involvement Screening Test (ASSIST V3.0), with 8 items in relation to the consumption of 9 substances, categorised into three risk levels: low (0-3 points), moderate (4-26 points) and high (more than 27 points).
Problem drug use1 yearDrug Abuse Screening Test (DAST-20), 20 questions with dichotomous answers (Yes/No) and a cut-off point of 5
Excessive alcohol consumption1 yearAlcohol Use Disorders Identification Test (AUDIT), with 10 questions, allows to identify: risky use (8-15 points), harmful use (16-19 points) and dependence (more than 20 points)
Nicotine dependence1 yearFagerström test. With six questions it classifies into mild (less than 4 points), moderate (4-6 points) or severe dependence (more than 7 points).
Waist and hip circumference1 yearThe waist and hip circumference shall be measured with a tape measure (cm).
Adherence to the Mediterranean diet1 yearDiet will be assessed with the Mediterranean Diet (MD) adherence questionnaire, developed in the PREDIMED project and consisting of 14 items with dichotomous responses.(points)
Sleep quality and quantity1 yearPittsburgh Sleep Quality Index (PSQI) which assesses the quality of sleep disturbance in the last month. It is composed of 19 items. The cut-off point for poor sleep quality is 5 points or higher. (points)
Sleep disruption1 yearThe Ford Insomnia Response to Stress Test, which assesses the likelihood of sleep disruption (points)

Countries

Spain

Contacts

Primary ContactManuel A Gomez-Marcos, Dr
magomez@usal.es923291100

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026