Visual Impairment
Conditions
Brief summary
The aim of the study is to assess visual function from neonatal age to 36 months of age in infants at risk of visual impairment due to brain lesion or ocular pathology
Interventions
None listed
Sponsors
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
2 Days to 36 Months
Healthy volunteers
No
Inclusion criteria
* Age between 34 weeks of post-menstrual age and 36 months of life in children born before 37 weeks gestational age * Genetic syndroms * Hypoxic Hischemic Encephalopathy * Brain malformation * Metabolic diseases * Ocular pathologies
Exclusion criteria
* Patients at low risk of developing neurological outcomes * Refusal of informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Early Visual Functions in Patients at Risk of Developing Cerebral Visual Impairment. A Pilot Study | 5 years | The score of the functional visual assessment will be obtained at neonatal age and at 1-3-6-9-12-18-24-36 months of life will be analysed at each age and compared to neurodevelopment findings using different scales according to age. These results will be related to the MRI total score (obtained by the sum of scores by site: cortex, basal ganglia, white matter and cerebellum, normal (0), mild abnormal (1), severely abnormal (2)). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation betwwen functional visual assessment score to MRI score | 5 years | Results of functional visual assessment will be related to the MRI total score (obtained by the sum of scores by site: cortex, basal ganglia, white matter and cerebellum, normal (0), mild abnormal (1), severely abnormal (2)). |
Countries
Italy
Contacts
Primary ContactDaniela Ricci, Medical Doctor
Outcome results
None listed