Predictors of Failure of Non-invasive Ventilation and High Flow Nasal Cannula

Predictors of Failure of Non-invasive Ventilation and High Flow Nasal Cannula in Acute Respiratory Failure Patients : the Standardized PaO2 / FiO2 Ratio (P /F-st), ROX Index and HACOR

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05864898

Enrollment

120

Registered

2023-05-18

Start date

2023-07-01

Completion date

2024-07-01

Last updated

2023-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Failure Patients on NIV and HFNC

Brief summary

Comparison between some predictors of failure of non-invasive ventilation and high flow nasal cannula.

Detailed description

Delayed intubation after NIV / HFNC failure is associated with high mortality rate in acute respiratory failure patients. There are Many factors to predict early failure but World still searching for new factors and comparing between each ;in order to eatablish best one that achieve the least mortality rate. Little studies about effiecacy of HACOR Score as a predictor of failure in HFNC patients. Little studies about effiecacy of ROX Index as a predictor of failure in NIV ventilating patients.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

Acute respiratory failure patients who need ventilatory Support either NIV or HFNC due to : 1. RR \> 25 cycle / min 2. using accessory muscles and paradoxical breath. 3. PaO2 / FiO2 ratio \< 300

Exclusion criteria

1. Absolute indication for intubation like coma, haemodynamically unstable… etc 2. Contr-indication of NIV like untreated Pneumothorax.

Design outcomes

Primary

Measure	Time frame	Description
Determine Golden time for intubation	1 year	Determine best time for intubation according to some predictors of failure of NIV and HFNC

Outcome results