Overweight and Obesity
Conditions
Brief summary
This observational study aims to detect serum levels of Developmental Endothelial Locus-1 (DEL-1), Platelet Count, and Soluble P-selectin (sP-sel) in Overweight and Obese Subjects. The main questions it aims to answer are: * Is there a difference in serum DEl-1 levels in overweight and obese subjects compared to normal subjects? * Are there any relations between serum DEL-1 levels, sP-sel, and platelet count in overweight and obese subjects ?
Interventions
DIAGNOSTIC_TESTPlatelet count
Platelet count in study groups
DIAGNOSTIC_TESTDevelopmental endothelial locus-1 (DEL-1)
Serum DEL-1 in study groups
DIAGNOSTIC_TESTsoluble P-selectin (sP-sel)
Serum sP-sel in study groups
Sponsors
Aswan University Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
MALE
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Male patients. * Age (18-65) years. * Healthy overweight and subjects.
Exclusion criteria
* Patients with cardiovascular diseases. * Diabetic patients. * Previous history of thrombo-embolic diseases. * Patients with hyperthyroidism. * Patients with any type of malignancy. * Underlying hepatic or renal failure. * Major surgery within 60 days.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Platelet count | 6 months | platelet count in venous blood samples in normal-weight, overweight, and obese subjects |
| Serum Developmental endothelial locus-1 levels | 6 months | Serum developmental endothelial locus-1 in normal-weight, overweight, and obese subjects |
| Serum Soluble P-selectin levels | 6 months | Serum Soluble P-selectin in normal-weight, overweight, and obese subjects |
Countries
Egypt
Outcome results
None listed