Sarcopenia
Conditions
Brief summary
To evaluate the effect of omega-3 supplementation combined with whey protein intake on lean mass and strength gains in older adults performing resistance exercise. Participants will be randomized into the 4 groups. The placebo group will receive 4 g per day of corn oil and 40 g per day of maltodextrin. The omega 3 + placebo group will receive 4 g per day of fish oil and 40 g per day of maltodextrin. The whey protein + placebo group will receive 40g per day of whey and 4g per day of corn oil. The omega 3 + whey group will receive 4g per day of fish oil and 40g per day of protein. All will perform the same exercise protocol for 12 weeks
Interventions
DIETARY_SUPPLEMENTPlacebo Group
The placebo group will receive 4 g per day of corn oil and 40 g per day of maltodextrin.
DIETARY_SUPPLEMENTWhey Protein + Placebo
The whey protein + placebo group will receive 40g per day of whey and 4g per day of corn oil.
DIETARY_SUPPLEMENTOmega 3 + Placebo
The omega 3 + placebo group will receive 4 g per day of fish oil and 40 g per day of maltodextrin.
DIETARY_SUPPLEMENTOmega 3 + Whey Protein
The omega 3 + whey group will receive 4g per day of fish oil and 40g per day of protein.
Sponsors
Federal University of Uberlandia
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
FEMALE
Age
60 Years to 85 Years
Healthy volunteers
Yes
Inclusion criteria
* Postmenopausal women (at least 1 year of menstrual interruption, self-reported); * To be able to practice strength exercises; * To be able to carry out supplementation; * Do not present physical, orthopedic or cardiovascular complications that prevent the performance of physical exercises; * No history of stroke or acute myocardial infarction; * Not being a smoker and/or alcoholic; * Do not perform hormone replacement therapy; * Do not use anti-inflammatory drugs; * To have normal kidney function; * To submit a medical certificate of health that proves that the individual is able to perform exercises.
Exclusion criteria
* Do not provide the necessary information for the development of the study; * Individuals with diseases previously diagnosed and undergoing treatment, such as type II diabetes mellitus, cancer, rheumatoid arthritis, high blood pressure, dyslipidemia, cardiovascular, and kidney and/or liver diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in lean mass (kg) using ultrasound and electrical bioimpedance in postmenopausal women | up to 12 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Changes in strength (kg) using dynamometer in postmenopausal women | up to 12 weeks |
Countries
Brazil
Contacts
Primary ContactErick P de Oliveira, PhD
Backup ContactErick P de Oliveira, PhD
Outcome results
None listed