Steroid Metabolism Disorder
Conditions
Keywords
Magnesium, Steroid avoidance
Brief summary
Steroid injections are used for interventional pain management. However, their side-effect of immunosuppression may increase the risk of infections. Magnesium is an alternative anti-nociceptive injection that may be used instead of steroids. Prospective observational study of patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using the numeric pain rating scale. Sleep score is measured using the Likert sleep scale. A change in the pain or sleep scores by 2-points is considered significant.
Detailed description
Corticosteroid injections are used for interventional pain management. The immunosuppression effect of steroid injection may increase the risk of infections. Magnesium is an alternative anti-nociceptive agent that may be used for interventional pain injection therapy, instead of steroids. Prospective observational clinical study of pain clinic patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using the numeric pain rating scale. Sleep score is measured using the Likert sleep scale. A change in the pain or sleep scores by 2-points is considered significant. Data analyzed with IBM® SPSS® Statistics 25 (IBM Corp, Armonk, NY); using Student's t-test, ANOVA, Pearson Chi-square test, and regression analysis. P-value \<0.05 is considered significant.
Interventions
DRUGMagnesium
Magnesium injection therapy
Sponsors
Salem Anaesthesia Pain Clinic
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 99 Years
Healthy volunteers
Yes
Inclusion criteria
* adult chronic pain patients * previous interventional injection therapy * consent for interventional injection therapy * good treatment compliance * regular sleep diary * regular pain diary * informed consent for diary review * consent for clinical record quality assurance review
Exclusion criteria
* organ insufficiency * cognitive disorder * inability to provide consent * major neuropsychiatric disorder * unreliable diary * poor treatment compliance * previous adverse/allergic reactions to magnesium
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain score, objective measurement using the validated Numeric Pain Rating scale | 12 weeks | Pain score, using the Numeric Pain Rating scale of 0 to 10, low scores indicate less pain, high scores indicate worse pain |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sleep quality score, objective measurement using the validated Likert sleep scale | 12 weeks | Sleep quality score, using the Likert sleep scale of 0 to 10, low scores indicate poor sleep, high scores indicate better sleep |
Countries
Canada
Contacts
Primary ContactOlu Bamgbade, MD,FRCPC
Outcome results
None listed