Neurosurgery, Risk Assessment, Venous Thromboembolism
Conditions
Brief summary
Validation of Clinical Prediction Model for Venous Thromboembolism Following Neurosurgery: A Multicenter, Prospective, and Cohort Study
Detailed description
A clinical prediction model for VTE after neurosurgical procedures during hospitalization has been developed and internally retrospectively validated. A multicenter, prospective cohort study is planned to validate this clinical prediction model again.
Interventions
DIAGNOSTIC_TESTClinical Prediction Model for Venous Thromboembolism Following Neurosurgery
This is a clinical prediction model that uses perioperative clinical indicators and laboratory tests to predict the occurrence of VTE after neurosurgery.
Sponsors
Capital Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. age \>18 years 2. underwent neurosurgical procedures during hospitalization 3. underwent preoperative ultrasound examination
Exclusion criteria
1. a patient with obvious bacterial or viral infection within the past two weeks before admission 2. a patient with venous thromboembolism within the past three months before surgery 3. a patient with anticoagulant therapy (direct oral anticoagulants, low molecular weight heparin) was administered continuously or intermittently before admission 4. a patient with a prior coagulation dysfunction
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Symptomatic or asymptomatic VTE | 2023.3-2023.7 | A combination of symptomatic or asymptomatic DVT and symptomatic or asymptomatic PE |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| DVT | 2023.3-2023.7 | A blood clot within a deep vein, typically in the thigh or leg, which is detected with compressible ultrasound, venography, impedence plethysmography, radiofibrinogen uptake scanning or autopsy based on the time of study. This outcome combines proximal or distal DVT of the leg, upper limb DVT |
| PE | 2023.3-2023.7 | Obstruction of a pulmonary artery or one of its branches that is usually produced by a blood clot which has originated in a vein of the leg or pelvis and traveled to the lungs, which is diagnosed by CT pulmonary angiography, ventilation-perfusion lung scanning pulmonary angiogram, or by autopsy or equivalent technology based on the time of study. This outcome combines saddle, lobar, segmental or subsegmental PE according to the anatomic location |
| Proximal DVT | 2023.3-2023.7 | Proximal DVT is a blood clot that is located in the popliteal, femoral, or iliac veins, which is detected with compressible ultrasound, venography, impedence plethysmography, radiofibrinogen uptake scanning or autopsy based on the time of study |
Countries
China
Contacts
Primary ContactDeshan Liu, Dr.
Outcome results
None listed