Regional Blocks, Renal Surgery
Conditions
Keywords
multimodal analgesia, regional blocks, renal surgeries
Brief summary
A multimodal analgesia regimen is suggested after nephrectomy, although some patients still report agonising pain. Regional anesthesia approaches may improve postoperative pain management and reduce the requirement for opioids after renal surgery.QLB provides early and rapid pain relief
Detailed description
In the immediate postoperative period, nerve blocks are considered a type of multimodal analgesia and have recently been proposed as analgesic options for patients undergoing open nephrectomy . Pain is defined as an unpleasant sensory and emotional experience associated with actual or potential tissue damage. The main barrier to early postoperative ambulation is postoperative pain, which also lengthens hospital stays and raises the risk of respiratory problems and venous thromboembolism. Therefore, strict perioperative pain management can have both immediate and long-term advantages . QLB provides early and rapid pain relief and allows early ambulation in certain patient populations. Multiple case studies also confirmed the QLB to be a rescue block after different surgical procedures. Complications associated with the performance of abdominal wall blocks are fortunately very rare. However, studies on the effect of anterior QLB on postoperative opioid consumption are scarce . Regional anesthesia is quickly moving toward using ultrasound guidance as the gold standard. The use of ultrasound has significant advantages over traditional treatments such as nerve stimulation and loss of resistance. The improved safety and efficacy that ultrasound brings to regional anaesthesia will help promote its use and realise the benefits that regional anaesthesia has over general anaesthesia, such as decreased morbidity and mortality, superior postoperative analgesia, cost-effectiveness, decreased postoperative complications and an improved postoperative course . The aim of the present study is to compare the effectiveness of ultrasound-guided preoperative to postoperative QLB on the postoperative pain scores after Radical nephrectomy.
Interventions
The patient will be placed in the lateral position, after sterilization.. QLB will be done using ultrasound, The probe will be positioned superior to the iliac crest, in the transverse orientation, at the posterior axillary line. The Shamrock sign will be identified at the L4 level, and the insulated nerve block needle will be advanced from posterior to anterior, through the QL muscle, until the needle tip is visualized in the interfascial plane between the QL muscle and psoas muscle. As the correct needle placement is confirmed with 2-3 mL of saline, 20 mL of 0.25% bupivacaine will be injected ensuring that the psoas muscle will be pushed deeply.
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Intervention model description
preoperative versus postoperative quadratous lumborum block in nephrectomy
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* o Patients aged between 18 - 60 years old. * Both sexes. * Physical Status: ASA I and II.
Exclusion criteria
* o Refusal of procedure or participation in the study . * Physical status: ASA III or above . * Infection at site of injection. * Psychiatric illness . * CNS Diseases like epilepsy, stroke …etc. * History or evidence of coagulopathy . * Allergies to drug used (Bupivacaine 0.5%). * Patients who suffered from allergy to local anesthetics . * Difficult visualization of the anatomy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The time to first postoperative rescue analgesia. | postoperative 24 hours | the first time patient ask for analgesia |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| total consumption of opioid in first 24 hours | first 24 hours postoperatively | amount of narcotic needed by patient in first 24 hours after nephrectomy |
Countries
Egypt
Contacts
PRINCIPAL_INVESTIGATORsanaa F wasfy
Ain Shams University
Outcome results
None listed