Colon Cancer
Conditions
Keywords
Colon cancer, MRI, Resection margin
Brief summary
The goal of this clinical trial is to explore the value of colon MRI in assessing the status of retroperitoneal resection margin (RPRM) for advanced colon cancer. The main questions it aims to answer are: * Concordance between MRI suspected RPRM positive and pathologically confirmed positive. * Can RPRM-positive patients undergo beyond complete mesocolic excision (CME) surgery in order to achieve R0 resection? Participants will undergo colon MRI examination and once MRI suspects RPRM positive, they will receive beyond CME surgery.
Interventions
PROCEDUREBeyond complete mesocolic excision surgery
If the participants were diagnosed with positive retroperitoneal resection margin (RPRM), they underwent beyond complete mesocolic excision surgery to ensure the R0 resection.
Sponsors
Peking University Cancer Hospital & Institute
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* primary colon adenocarcinoma confirmed by biopsy * preoperative CT suspecting retroperitoneal resection margin (RPRM) positive * received colon MRI scan * underwent beyond complete mesocolic excision surgery * sufficient clinical and pathological results
Exclusion criteria
* combined with other malignant tumors * simultaneous distant metastasis * definite invaded other organs or structures (T4b tumors)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Coincidence rate with pathological result | within 2 weeks after surgery | Coincidence rate between MRI diagnosed retroperitoneal resection margin and pathologically confirmed positive |
Countries
China
Contacts
Primary ContactZhen Guan, MD
Outcome results
None listed