Neonatal Cyanosis Due to PDA Dependent Pulmonary Circulation
Conditions
Brief summary
After echocardiography confirmation of PDA dependent pulmonary circulation in cyanotic neonates, catheter-guided PDA stent implantation will be done. Under general Anasthesia and after discontinuation of prostaglandin 4-6 hours before procedure, obtain vascular access and unfractionated heparin is given, then duct is accessed via a cut pig-tail or Judkins right \[JR\] catheter, and is crossed by PTCA wire to be carefully placed in the left or right branch pulmonary arteries, choose proper stent diameter and length, place the stent and confirm it's position, NICU admission for the neonate with heparin infusion for 24-48 hrs and acetylsalicylic acid is given then follow up the patient by pulse oximeter and echocardiography
Interventions
DEVICECatheter-guided PDA stent implantation
PDA stent is the primary treatment for patients with duct-dependent pulmonary circulation. It serves as a temporary bridge for later surgical repair by keeping the duct patent to improve oxygen saturation
Sponsors
Sohag University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
1 Hours to 2 Months
Healthy volunteers
No
Inclusion criteria
Neonates and young infants with duct dependent pulmonary circulation
Exclusion criteria
* Untreated sepsis. * Coagulopathy. * PDA dependent systemic circulation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Oxygen saturation | Change in oxygen saturation within 24 hours | Using pulse oximeter to assess oxygen saturation |
| Evaluation of duct patency | 1 month | Using echocardiography assess flow through the duct |
Countries
Egypt
Contacts
Primary ContactSomaia S Mahmoud, Master
Outcome results
None listed