Neuromuscular Ultrasonography Assessment of Optic Nerve in Systemic Lupus Eryhematosus

Neuromuscular Ultrasonography Assessment of Optic Nerve in SLE

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05853003

Enrollment

140

Registered

2023-05-10

Start date

2022-01-01

Completion date

2023-04-30

Last updated

2024-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Optic Neuropathy

Brief summary

assessing the role of neuromuscular ultrasound in optic nerve involvement in systemic lupus patients.

Detailed description

Evaluating the role of neuromuscular ultrasound in optic nerve involvement in systemic lupus patients.by measuring the diameter of optic nerve at certain site and comparing it to healthy subjects measurements and to asses NMUS ability to detect optic neuropathy in lupus patients in comparison to conventional techniques including opthalmologist evaluation and visual evoked potential

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

17 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Adult * group of SLE patients, who fulfilled Systemic Lupus International Collaborating Clinics classification criteria for SLE (SLICC) with or without symptoms of optic neuropathy * another group of apparently healthy subjects with no. history of chronic conditions

Exclusion criteria

* Any patient with optic neuritis due to causes other than lupus was excluded from the study: ex. * Post traumatic neuropathy * Purely degenerative neuropathy * Diabetic neuropathy * Toxic neuropathy * Neuropathies related to infections * Drug induced neuropathy e.g: quinine and some antibiotics, ethambutol * Infections e.g. measles, mumps, Lyme disease, etc. * Other Autoimmune diseases like sarcoidosis, B.D * Tumor causing Inc. intracranial tension.

Design outcomes

Primary

Measure	Time frame	Description
comparing diameter (in mm2) of optic nerve in SLE patients and compare them to healthy subjects	over 1 year	comparing diameter (in mm2) of optic nerve in SLE patients and compare them to healthy subjects

Countries

Egypt

Outcome results