COPD Exacerbation
Conditions
Brief summary
To identify clinical characteristics on presentation which predict differential outcomes in patients with exacerbation of COPD.
Detailed description
Exacerbations of COPD (ECOPD) are heterogenous but are often considered as a single clinical entity. Clinical characteristics on presentation may predict outcome of patients with ECOPD. DECAF score was previously proposed to predict in-hospital mortality but has not been validated in Asian subjects. ROME classification was recently proposed to better risk stratify ECOPD according to symptoms, physiological parameters and laboratory findings on admission, but no prospective validation study is available so far. This study aims to identify clinical characteristics on presentation to predict outcome of patients with ECOPD.
Interventions
OTHERObservation only
Observation only
Sponsors
Pamela Youde Nethersole Eastern Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Inclusion criteria
* Background history of COPD, defined by the GOLD 2023 guidelines * Presented with exacerbation of COPD, defined by the GOLD 2023 guidelines * Age \>= 18 years old * Informed consent available
Exclusion criteria
* Age \< 18 years old * No informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| In-hospital mortality | 3-month | Number of patients died during hospitalization of ECOPD |
| 3-month mortality | 3-month | Number of patients died 3 months after ECOPD |
| Recurrent ECOPD | 3-month | Number of patients with recurrent ECOPD post-discharge |
| Viral etiology | 3-month | Frequency of various viral etiology identified during ECOPD |
| Bacterial etiology | 3-month | Frequency of various bacterial etiology identified during ECOPD |
Countries
Hong Kong
Outcome results
None listed