Passive Transmission of Maternal and Infant Antibodies
Conditions
Brief summary
At present, there is no relevant research focusing on children's acquisition of novel coronavirus antibodies through maternal passive transmission. Therefore, this study assessed the changes of maternal passive transmission of COVID-19 antibodies by monitoring the specific antibodies of COVID-19 in young children; This will lay a foundation for further exploring the risk of COVID-19 infection in children and formulating immune prevention strategies.
Interventions
BIOLOGICALsars-cov-2 vaccine or infection
Whether to vaccinate COVID-19 vaccine, or infect with sars-cov-2
Sponsors
Children's Hospital of Chongqing Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
0 Months to 2 Years
Healthy volunteers
Yes
Inclusion criteria
1. Children aged 0-2; 2. No history of blood transfusion, chemotherapy, or related immunosuppressive therapy; No immune system related diseases;
Exclusion criteria
Not willing to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| SARS-CoV-2 IgG | duration of time over which each participant could be 6-month to 12-month | ELISA detection of SARS-CoV-2 IgG antibody levels |
| SARS-CoV-2 neutralizing antibody | duration of time over which each participant could be 6-month to 12-month | detection the level of SARS-CoV-2 neutralizing antibody |
Countries
China
Contacts
Primary ContactYuting Yang, Ms
Outcome results
None listed