Analgesia
Conditions
Brief summary
Postoperative pain management is considered an integral part of perioperative care in patients undergoing thoracotomy. In order to reduce these complications, multiple regional techniques have been developed for thoracotomy including Intercostal nerve block, Erectospinae plane block and serratus block. Multiple adjuvants have been used in regional analgesia including adrenaline,clonidine,magnesium sulphate,dexmedatomidine and opoids.
Interventions
DRUGBupivacaine
Bupivacaine 0.25%
DRUGBupivacaine + Magnesium
Bupivacaine 0.25% + Magnesium
Bupivacaine 0.25% + Dexmedetomidine
Sponsors
National Cancer Institute, Egypt
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Caregiver, Investigator)
Masking description
Double blinded
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Age from 18 to 65 years. * Male and female sexes. * ASA I-II.,III * Cancer patients undergoing thoracotomy incisions * Body mass index (BMI) from 18.5 to 30 kg/m2
Exclusion criteria
* Patient refusal * Known allergy to any of the used drugs * Low platelet count, any coagulation defect
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total postoperative morphine consumption | First 24 hours postoperatively | Total dose of morphine needed postoperatively in the first 24 h |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time to first postoperative rescue analgesia. | First 24 hours postoperatively | Time to first postoperative rescue analgesia. |
Countries
Egypt
Contacts
CONTACTWalaa Y Elsabeeny, MD
CONTACTAhmed A Mohamed, MD
PRINCIPAL_INVESTIGATORWalaa Y Elsabeeny, MD
Assistant professor of Anesthesia and Pain Management, National Cancer Institute, Cairo University
STUDY_DIRECTORAhmed A Mohamed, MD
Professor of Anesthesia,Surgical intensive care and Pain management,Faculty of medicine
Outcome results
None listed