Chemotherapy Effect, Chemotherapy-induced Nausea and Vomiting, Pediatric Cancer
Conditions
Keywords
acupuncture, ear acupuncture, CINV, cancer, press needle
Brief summary
Chemotherapy is a cancer therapy performed on advanced cancer with quite good success, but this therapy has quite a lot of side effects. Chemotherapy induced nausea and vomiting or commonly known as CINV, is a condition of nausea and vomiting experienced by cancer patients undergoing chemotherapy, with a prevalence of around 80% of all patients undergoing chemotherapy, and 40% has the potential to become severe. This study aims to determine the efficacy of a new acupuncture modality, namely the press needle, in preventing CINV symptoms in pediatric patients with cancer undergoing chemotherapy.
Detailed description
The study was conducted using a randomized controlled clinical trial (RCT) design in 64 pediatric cancer patients undergoing chemotherapy who were randomized into 2 groups, namely: (1) standard medical therapy as the control group; and (2) a combination of standard therapy with press needle acupuncture as the treatment group. The ear acupuncture points used are Shenmen and Stomach, and one body acupuncture point is PC6. Outcome measurements were carried out in the form of the RINVR questionnaire to assess the intensity of nausea and vomiting measured at 4 times: (1) 12 hours before chemotherapy; (2) 12 hours after chemotherapy; (3) 3 days after chemotherapy; (4) 7 days after chemotherapy.
Interventions
DEVICEPress needle acupuncture
Press needle acupuncture is a modality of acupuncture using tiny and very thin needles.
DEVICEPlesterin
The plaster used is a round plaster that resembles the shape of an acupuncture press needle.
Sponsors
Mashhad University of Medical Sciences
Indonesia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
6 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* Pediatric patients with cancer who are undergoing chemotherapy. * Age 6 - 18 years. * Patients with platelet counts \> 20,000/μL and neutrophil values \> 1,000/μL. * Willing to follow the research.
Exclusion criteria
* Patients with local infection in the puncture area. * Patients with anatomic abnormalities in the auricle. * Did not complete the acupuncture therapy until it was finished (three days after chemotherapy).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rhodes Index of Nausea, Vomiting, and Retching (RINVR) questionnaire | 9 days | Method instrument for assessing nausea and vomiting consisting of eight statements |
Countries
Indonesia
Outcome results
None listed