Alveolar Osteitis
Conditions
Keywords
alveolar osteitis, Collagen sponge, Impacted lower third molar
Brief summary
The goal of this randomized controlled trial is to compare pain, mouth opening, and alveolar osteitis following surgical extraction of bilateral symmetrical impacted lower third molars using two types of wound closures. Collagen plugs will be applied in the sockets of the study side followed by suture, while the controlled side will be sutured without a collagen plug. The study will include 40 patients aged between 18- 40 years old, medically fit (ASA1), who have bilateral symmetrical impacted lower third molars and visit the oral surgery clinics of King Saud Medical City for extraction. The main question is Does intra-alveolar collagen application after surgical extraction of impacted lower third molars reduce the incidence of alveolar osteitis?
Interventions
OTHERApplication of a collagen sponge after surgical extraction of impacted 3rd molar
Application of a collagen sponge after surgical extraction of impacted 3rd molar
OTHERNo collagen sponge application after surgical extraction of impacted 3rd molar
No collagen sponge application after surgical extraction of impacted 3rd molar
Sponsors
Riyadh Colleges of Dentistry and Pharmacy
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Masking description
The participants (patients) will not be informed about which side will recieve the collagen
Intervention model description
The patients will have surgical extraction of impacted 3rd molars for both sides with a gap of 3 weeks. The study side will receive a collage sponge after extraction followed by sutures. The controlled side will have sutures without a collagen sponge.
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
Forty patients aged between 18- 40 years old, ASA1, who have bilateral symmetrical impacted lower third molars and visit the oral surgery clinics of King Saud Medical City for extraction.
Exclusion criteria
Uncontrolled systemic diseases, diabetes, bone diseases, smokers, epinephrine contraindications, pregnant women, breastfeeding women, and those who were using oral contraceptives. Other
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pre-extraction Pain score | Pre-extraction | Pain measurement by VAS (0-10). 0: no pain. 10: worst pain |
| Pre-extraction Halitosis | Pre-extraction | Halitosis in reported in the presence of a bad odor that is smelled by the investigator during the patient's speech |
| Pre-extraction Mouth opening | Pre-extraction | Maximum Mouth opening is taken by a caliber |
| Pain score Day3 | 3 days after extraction | Pain measurement by VAS (0-10). 0: no pain. 10: worst pain |
| Pain score Day7 | 7 days after extraction | Pain measurement by VAS (0-10). 0: no pain. 10: worst pain |
| Mouth opening Day7 | 7 days after extraction | Maximum Mouth opening is taken by a caliber |
| Halitosis Day7 | 7 days after extraction | Halitosis in reported in the presence of a bad odor that is smelled by the investigator during the patient's speech |
| Alveolar osteitis | After 3 days of extraction | is diagnosed if the patient complains of pain (more than 5) between day 2 and day 4 with empty sockets and food debris, with or without halitosis |
Countries
Saudi Arabia
Contacts
Primary ContactNedal A Abu-Mostafa, Assistant P
Outcome results
None listed