Effectiveness of Combining Erector Spinea Block With Non Opioid Infusions as Opioid Free Anesthesia in Spine Surgeries.

Assistant Professor of Anesthesia, Intensive Care and Pain Management

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05850468

Enrollment

140

Registered

2023-05-09

Start date

2023-05-31

Completion date

2023-11-30

Last updated

2023-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opioid Use, Spine Fusion

Keywords

multimodal analgesia, regional blocks, spine surgeries

Brief summary

opioid free anesthesia consists of combination of pharmacological and non pharmacological modalities that target different pathways of pain mechanism. combining myofascial plane blocks with infusion of adjuvants such as lidocaine or dexmedetomidine can offer equivalent intraoperative hemodynamic stability compared to that of opioid with better pain control postoperatively. this study will investigate the efficacy of combined erector spina block with lidocaine and dexmedetomidine infusion as opioid sparing anesthesia in spine surgeries

Detailed description

patients who will undergo spine surgery will be allocated into two groups. after general anesthesia, bilateral erector spine block will be applied in both groups. group A will have intraoperative fentanyl infusion and group B will have lidocaine and dexmedetomidine infusion in 50 ml syringe till end of surgery

Interventions

DRUGlidocaine 2% and dextometometidine infusion after general anesthesia and erector spinea block

intraoperative non opioid infusion in experimental group

DRUGfentanyl infusion after general anesthesia and erector spinea block

intraoperative opioid infusion in active comparative group

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

\- spine surgery ASAI,II

Exclusion criteria

* revision surgery hypotension bradycardia

Design outcomes

Primary

Measure	Time frame	Description
number of patients (percentage) having intraoperative systolic hypertension	during operation(intraoperatively)	blood pressure more than 160 mmhg
number of patients(percentage) having tachycardia	during operation(intraoperatively)	heart rate more than 100 beat /minute

Secondary

Measure	Time frame	Description
VAS score	every 30 minutes for 2 hours postoperatively	score from 0 to 10, 0 is no pain and 10 the worst pain
incidence of bradycardia	intraoperatively	heart rate less than 45 beat per minute

Countries

Egypt

Contacts

Primary Contactsanaa wasfy, professor

sanaawasfy@gmail.com01061262757

Backup Contactwael behairy, professor

wailbehairy@yahoo.com01282269727

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026