Role of Early Point of Care Ultrasound in Management of Sepsis in Emergency Department

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05849194

Enrollment

200

Registered

2023-05-08

Start date

2023-08-01

Completion date

2024-07-31

Last updated

2024-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Keywords

Point of care ultrasound, Sepsis, Emergency department

Brief summary

Aim of the study is to determine the diagnostic accuracy of point-of-care ultrasound and to determine its role in sepsis management .

Detailed description

Two groups of patients will be studied one group will undergo POCUS examination and the other will not undergo POCUS examination then comparison between them will be done regarding accuracy of diagnosis and time taken to reach diagnosis.

Interventions

DIAGNOSTIC_TESTPOCUS examination

Point of care ultrasound examination

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

19 Years to 100 Years

Healthy volunteers

Inclusion criteria

* Adult patients admitted to the Emergency Department (ED) of Alexandria Main University Hospital (AMUH) with sepsis. * Patients presented with septic shock.

Exclusion criteria

* Age less than 18 * Trauma patients. * Pregnant females. * Patients with terminal malignancy. * Patients taking immunosuppressive drugs or chemotherapy.

Design outcomes

Primary

Measure	Time frame	Description
Diagnostic accuracy of POCUS approach compared with the definitive diagnosis.	8 months	The study will include two groups of patients, POCUS group that will undergo point of care ultrasound (POCUS)examination in addition to clinical evaluation and laboratory investigations and control group that will not undergo POCUS examination but only undergo clinical evaluation and laboratory investigations. Both groups will be compared regarding proportion of accurate diagnosis (at emergency department)in relation to the final diagnosis that will be obtained after patient undergo further imaging techniques to search for sepsis such as chest X-ray or CT to look for chest infection and CT abdomen to confirm intra-abdominal sepsis. Unlike trauma, dyspnea and shock up till now there is no validated POCUS protocol to evaluate patients with sepsis.

Secondary

Measure	Time frame	Description
Time taken to reach diagnosis in both groups	8 months	Evaluation of the difference between two groups regarding time taken to reach diagnosis

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026