Infertility, Female, Vitamin D Deficiency
Conditions
Brief summary
The goal of this prospective cohort study is to learn about the overall and seasonal prevalence of vitamin D insufficiency and its determinants in a population of women with infertility who will go through in vitro fertilization in Sweden. The main questions it aims to answer are: * What is the prevalence of vitamin D insufficiency? * What are the determinants of this insufficiency? Participants will be asked to complete a questionnaire validated for dietary assessment of vitamin D intake and sun exposure habits and they will leave a blood sample for measurement of 25(OH)D concentration. Researchers will compare the in vitro fertilization outcomes between women with vitamin D insufficiency and sufficiency to see if there is any difference.
Interventions
None listed
Sponsors
Vastra Gotaland Region
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* women aged 18-38 years, who will go through in vitro fertilization for infertility.
Exclusion criteria
* women who will go through pre-implantation genetic testing * women who will go through sperm- or oocyte donation treatment * Fertility preservation cycles
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of vitamin D insufficiency | September 2020 - August 2021 | Overall and seasonal prevalence of vitamin D insufficiency |
| Determinants of vitamin D insufficiency | September 2020 - August 2021 | Determinants (dietary, sun exposure habits) of vitamin D insufficiency |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| In vitro fertilization outcomes | September 2020 - August 2021 | Pregnancy outcomes (biochemical pregnancy, clinical pregnancy, miscarriage, live birth) after in vitro fertilization between women with and without vitamin D insufficiency. |
Countries
Sweden
Outcome results
None listed