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Assisting Pulmonary Disease Diagnosis With Ophthalmic Artificial Intelligence Technology

Assisting Pulmonary Disease Diagnosis With Ophthalmic Artificial Intelligence Technology

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05847894
Enrollment
10000
Registered
2023-05-08
Start date
2020-06-29
Completion date
2027-05-01
Last updated
2026-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Artificial Intelligence, Ophthalmological Diagnostic Techniques, Pulmonary Diseases

Keywords

Pulmonary Diseases, Ophthalmological Diagnostic Techniques, Artificial intelligence

Brief summary

This study intends to collect ophthalmologic examination results, pulmonary examination results and related indexes from patients with pulmonary disease and control populations, and combine big data analysis and artificial intelligence technology to explore whether new methods can be provided for early screening strategies for pulmonary disease with the aid of ophthalmologic examination, and thus assist in identifying the types of pulmonary disease and determining disease prognosis.

Interventions

DIAGNOSTIC_TESTOphthalmic examination

Various ophthalmic examination modalities, including slit lamp photography, fundus photography, optical coherence tomography imaging and optical coherence tomography angiography, etc.

DIAGNOSTIC_TESTPulmonary Examination

Various pulmonary examination modalities, including radiography, chest CT, pulmonary function measurement, etc.

Sponsors

Zhongshan Ophthalmic Center, Sun Yat-sen University
Lead SponsorOTHER
The First Affiliated Hospital of Guangzhou Medical University
CollaboratorOTHER
Shenzhen Third People's Hospital
CollaboratorOTHER
Guangzhou Kindness Health Care Center (Guangzhou Jiubang Shanxin Clinic Ltd), Guangzhou, China
CollaboratorUNKNOWN

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* Those aged ≥18 years; or those aged \<18 years who can cooperate with the relevant examination and are accompanied and informed by a guardian; * People with respiratory-related diseases who were to undergo pulmonary examination, or those who volunteered to participate in the trial through publicity recruitment; * expected survival time of 3 months or more; * Those with no previous serious underlying disease and no history of serious eye disease; * Those who can cooperate with ophthalmologic and pulmonary-related examinations and have regular follow-up examinations; * Those who gave informed consent to the study prior to the trial and voluntarily signed the informed consent form; * Other conditions that can be included in the study as judged by the investigator.

Exclusion criteria

* Patients who are unable to complete ophthalmology or pulmonary-related examinations and regular follow-ups due to serious diseases, trauma or surgery (serious ophthalmology diseases such as extremely poor vision that cannot be fixed, ocular atrophy, severe refractive interstitial clouding that prevents fundus photography, etc.); * People with poor compliance due to various reasons such as alcohol or drug dependence, or mental disorders; * Those without informed consent; * Other conditions judged by the investigator to be unsuitable for participation in the trial.

Design outcomes

Primary

MeasureTime frameDescription
Area Under the Receiver Operating Characteristic curveThrough study completion, an average of 1 yearDetermining the accuracy of diagnosing pulmonary disease with ophthalmic examination

Countries

China

Contacts

CONTACTWeixing Zhang, M.D.
zhangwx98@mail2.sysu.edu.cn8615602211660

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 13, 2026