Benign Paroxysmal Positional Vertigo, BPPV, Inner Ear Disease, Labyrinth Diseases, Vertigo, Vestibular Diseases, Vestibular Disorder
Conditions
Keywords
TRV reposition chair, Dix-Hallpike maneuver, Supine Roll Test
Brief summary
The aim is to investigate the accuracy of manual diagnostics of benign paroxysmal positional vertigo (BPPV) by comparing it to BPPV diagnostics in mechanical rotational chair (TRV chair). VNG (videonystagmography) goggles will be used in both scenarios. Furthermore, the investigators will examine the importance of angulation and velocity in relation to the diagnostic outcome.
Detailed description
Open-label, randomized controlled trial with cross over comparing manual bedside BPPV diagnostics with diagnostics in a mechanical rotational chair (TRV chair) when using VNG goggles in both scenarios. Patients with a history of positional vertigo will be considered for enrollment and randomized to which diagnostic modality they begin with. Each subject will wait for minimum 30 minutes between the two diagnostics.
Interventions
DIAGNOSTIC_TESTBPPV diagnostic
Supine Roll Test and Dix-Hallpike Test
DEVICETRV chair
Mechanical rotational chair
DEVICEVNG goggles
Goggles for video nystagmography
DEVICEIMU sensor
A sensor that measures triaxial acceleration and triaxial angular velocity.
PROCEDUREManual BPPV diagnostics
Bedside BPPV diagnostics
Sponsors
Aalborg University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age above 18 years * Classic BPPV-patient history (short lasting (\<1 minute) positional rotatory vertigo, no accompanying tinnitus or hearing loss, and no focal neurological findings. * Understand written and spoken Danish
Exclusion criteria
* Pregnancy * Weight ≥ 150 kg and or Height ≥ 2m * Neck and spine immobility to a degree where MD on examination bed is impossible * Insufficient cooperation during diagnostic testing * Sedative antihistamines taken within the past seven days * Comorbidities: Heart failure (EF \< 40), known cerebral aneurysm, cerebrovascular events (\<3 months) or dissection disease * Spontaneous or gaze evoked nystagmus
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic Accuracy | 2 year | Sensitivity, specificity, positive predictive value and negative predictive value of bedside examination (index-test). Gold standard is diagnostics in the TRV chair. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Head angulation during diagnostic bedside examination. | 2 year | Angulation of the head during diagnostic bedside examination will be measured using an IMU sensor. Data will be presented as the difference in head angulation compared to the ideal angulation descriped for the diagnostic tests. |
| Angular velocity during diagnostic bedside examination | 2 year | Angular velocity of the head movements during diagnostic bedside examination will be measured using an IMU sensor. Data will be presented as mean velocity and peak velocity. |
Countries
Denmark
Outcome results
None listed