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Radiomic Modeling in Differentiating Uncomplicated From Complicated Acute Appendicitis

Development and Validation of an Individualized Nomogram to Differentiate Uncomplicated From Complicated Acute Appendicitis in Adults: a Multicenter Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05843630
Enrollment
250
Registered
2023-05-06
Start date
2023-01-03
Completion date
2023-12-03
Last updated
2023-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Appendicitis

Keywords

acute appendicitis, diagnosis, nomogram

Brief summary

Non-operative management (NOM) with antibiotics may be a safe alternative to surgery for uncomplicated appendicitis, but preoperative differentiation between uncomplicated and complicated appendicitis is challenging. The study aimed to develop a clinical-radiomics nomogram to distinguish uncomplicated from complicated appendicitis.

Interventions

DIAGNOSTIC_TESTwithout

without

Sponsors

Kecheng Zhang
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Pathologically diagnosed as acute appendicitis after appendectomy between January 2021 and December 2022.

Exclusion criteria

* age less than 18 years (no upper age limit); * without CT examination within a week before surgery; * difficult to outline the contours of the appendix due to inflammatory exudate; * lack of clinical information.

Design outcomes

Primary

MeasureTime frameDescription
Accuracy of clinical-radiomic model for differentiating complicated from uncomplicated appendicitisJanuary 2021 to December 2022ROC curve will be plotted and the area under ROC curve will be compared

Countries

China

Contacts

Primary ContactLI LI
1192225348@qq.com13210613213

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026