Painless Vainal Labour
Conditions
Brief summary
compare the effect of intravenous and epidural dexmetomidine as an adjuvant to local anesthetics in epidural labor analgesia in normal labor
Interventions
DRUGDexmedetomidine Injection [Precedex]
interventional drug will be administred either intravenously or epidurally
DRUGBupivacaine Injection
intervention drug will be administred epidurally
Sponsors
Menoufia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
FEMALE
Age
19 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Full term (≥ 37 weeks) healthy primigravida parturients ASA2 * with single fetus scheduled for vaginal delivery * with cephalic presentation * requesting labor analgesia.
Exclusion criteria
* Allergy to dexmetomidine.(based on previous history) * Cardiac conduction abnormalities.(all degrees of heart block , tachyarrythmias) * Twins. * Malpresentation. * Preeclampsia or gestational hypertension * Uncontrolled diabetes HBA1c ≥ 6.5% * Uncontrolled renal failure * Uncontrolled liver disease * Bleeding tendency or coagulopathy. * Contraindication or patient refusal to epidural block. * Body mass index ≥ 35.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pain relief | at 30 min after induction of block | VAS score from 0 to 10 will be assesed |
Countries
Egypt
Contacts
Primary Contactmostafa S mansour, MD
Outcome results
None listed