Retrospective Study of Germ Cell Tumors of the Central Nervous System

Single-center Retrospective Study of Germ Cell Tumors of the Central Nervous System

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05836701

Enrollment

500

Registered

2023-05-01

Start date

2023-06-01

Completion date

2024-12-31

Last updated

2024-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Germ Cell Tumor of CNS

Brief summary

Retrospectively analyzing the epidemiological and clinical characteristics, treatment, recurrence, prognosis and prognostic factors of the germ-cell tumors of central nervous system in a single center.

Detailed description

Clinical data of patients with germ-cell tumors of central nervous system who were treated in the Department of Neuro-oncology, Sanbo Brain Hospital Capital Medical University between January 2007 and December 2022 were retrospectively collected, and the epidemiological and clinical characteristics, treatment, recurrence, prognosis and prognostic factors of the disease were analyzed.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Clinically or pathologically diagnosed as germ cell tumor of the central nervous system. * Have received antitumor therapy. * Patients who were clinically diagnosed based on neuroimaging characteristics and response to radiotherapy or chemotherapy were allowed for enrollment.

Exclusion criteria

* Patients with missing key information such as tumor location, surgical, chemotherapy and radiotherapy data, and post-treatment evaluation.

Design outcomes

Primary

Measure	Time frame
epidemiological characteristics	1 year
treatment regimen	1 year
relapse pattern	1 year
prognostic factor	1 year

Countries

China

Outcome results