Degenerative Mitral Valve Disease, Mitral Regurgitation
Conditions
Brief summary
Mitral regurgitation is a pathology affecting the left atrioventricular valve that causes a volumetric and pressure overload in the left chambers due to the loss of unidirectionality normally guaranteed by the cardiac valve system. The gold standard for severe mitral regurgitation is currently mitral valve plastic surgery. Edge to edge, on the other hand, allows shorter CEC and aortic clamping times and does not require significant surgical experience in the field of mitral valve repair, therefore edge to edge could be an excellent strategy in patients suffering from mitral regurgitation caused by P2 prolapse when quadrangular resection cannot be performed. The main objective of the present study is to examine the medium to long-term outcomes (in terms of survival and plastic outcomes) of patients undergoing central edge-to-edge to treat posterior flap pathology (P2).
Interventions
PROCEDURECentral edge-to-edge
Suture of free margins of the mitral leaflets in central position to restore coaptation
Sponsors
Michele De Bonis
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Mitral regurgitation with degenerative etiology * Mitral pathology exclusively dependent on P2 * Surgical creation of a double mitral valve orifice with or without a ring as the only mitral valve repair technique.
Exclusion criteria
\- Other mitral regurgitation etiologies (eg. functional, radiation-induced, rheumatic...)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MR 2+ or more recurrency | through study completion, a minimum of 2 years |
Secondary
| Measure | Time frame |
|---|---|
| Reintervention | through study completion, a minimum of 2 years |
Countries
Italy
Outcome results
None listed