Oxygen Deficiency
Conditions
Brief summary
Anesthesia induction is associated with hemodynamic imbalances that can affect the blood flow to major organs. Moreover it can result in deoxygenation as well. During standard anesthesia induction the patient is manually ventilated with a circle-valve-mask system until the effect of muscle relaxant shows of. Near-infrared spectroscopy (NIRS) is a modification of a well-known peripheral pulse oxymetry that is used in the detection of the regional oxygen saturation (rSO2) in organs, including brain, liver, muscle, and intestines. In this study we will compare the regional oxygenation status of the patients during anesthesia induction in which either standard manual ventilation or mechanical ventilator-assisted ventilation was performed. AutoFlow(R) mode of Draeger-Perseus mechanical ventilator will be used for the ventilator-assisted ventilation.
Interventions
BEHAVIORALMechanical ventilator-assisted ventilation
After the intravenous anesthesia induction, mechanical ventilator-assisted ventilation with AutoFlow mode of the anesthesia machine (Draeger-Perseus) will be applied before intubation.
Sponsors
Marmara University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
5 Years to 10 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anaesthesiologists (ASA) physical status I-II
Exclusion criteria
* ASA III or above * Congenital or traumatic brain injury * Allergy to NIRS probe material * Cardiac or vascular disease, including heart failure or hypertension * Difficult mask ventilation and difficult intubation * Thoracic surgery * Head and neck surgery * Emergency surgery * Obesity
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| NIRS_-1 | 60 seconds before induction. | Serebral oxygenation status measured by near-infrared spectroscopy device (INVOS oximeter, Somanetics, Troy, MI, USA). |
| NIRS_0 | At the start of anesthesia induction. | Serebral oxygenation status measured by near-infrared spectroscopy device (INVOS oximeter, Somanetics, Troy, MI, USA). |
| NIRS_0.5 | 30 seconds after the anesthesia induction. | Serebral oxygenation status measured by near-infrared spectroscopy device (INVOS oximeter, Somanetics, Troy, MI, USA). |
| NIRS_1 | 60 seconds after the anesthesia induction. | Serebral oxygenation status measured by near-infrared spectroscopy device (INVOS oximeter, Somanetics, Troy, MI, USA). |
| NIRS_1.5 | 90 seconds after the anesthesia induction. | Serebral oxygenation status measured by near-infrared spectroscopy device (INVOS oximeter, Somanetics, Troy, MI, USA). |
| NIRS_2 | 120 seconds after the anesthesia induction. | Serebral oxygenation status measured by near-infrared spectroscopy device (INVOS oximeter, Somanetics, Troy, MI, USA). |
Countries
Turkey (Türkiye)
Outcome results
None listed