Treatment of Posterior Benign Paroxysmal Positional Vertigo With Mechanical Rotational Chair.

Treatment of Posterior Benign Paroxysmal Positional Vertigo With Mechanical Rotational Chair: A Randomized Controlled Trial Comparing Epley and 360° Maneuvers.

Status

Active, not recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05834452

Enrollment

128

Registered

2023-04-28

Start date

2023-04-12

Completion date

2026-04-30

Last updated

2025-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Paroxysmal Positional Vertigo, BPPV

Keywords

Benign Paroxysmal Positional Vertigo, Vertigo, Dizziness, Vestibular Diseases, Epley Maneuver, TRV chair, Mechanical Rotational Chair

Brief summary

Comparison of treatment efficacy of Epley maneuver and 360 maneuver in a mechanical rotational chair (TRV chair) in patient with posterior benign paroxysmal positional vertigo (BPPV).

Detailed description

Open-label, randomized controlled trial comparing the Epley maneuver with the 360 maneuver using the TRV chair in both scenarios. Patients diagnosed with posterior BPPV will be randomized to receive treatment with either the Epley maneuver or the 360 maneuver.

Interventions

PROCEDUREThe Epley Maneuver

5 step procedure where the patient: 1. Sits upright in a neutral position 2. Rotate 45° towards the affected side around the yaw axis and then ro-tate 135° backward around the pitch axis 3. Rotated 90° towards the unaffected side around the yaw axis 4. Rotate a further 90° toward the unaffected side around the yaw axis 5. Rotates back to an upright position with a 135° backward rotation around the pitch axis.

PROCEDUREThe 360 Degree Maneuver

5 step procedure where the patient: 1. Sits upright in a neutral position 2. Rotate 45° towards the affected side around the yaw axis and then ro-tate 135° backward around the pitch axis 3. Rotate a further 90° backward around the pitch axis (total 225°) 4. Rotate a further 90° backward around the pitch axis (total 315°) 5. Rotate back to an upright position with an additional 45° backward rota-tion around the pitch axis (total 360°).

DEVICEMechanical rotational chair

TRV chair

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age above 18 years * Confirmed unilateral p-BPPV (canalithiasis and cupulolithiasis) * Understand written and spoken Danish

Exclusion criteria

* Pregnancy * Weight ≥ 150 kg and or Height ≥ 2m * Not possible to attend follow-up visits * Insufficient cooperation during diagnostic testing or treatment in the mechanical rotational chair * Have received treatment for BPPV in a mechanical rotational chair within the last 6 months * Sedative antihistamines are taken within the past 7 days * Comorbidities: Heart failure (EF\<40), known cerebral aneurysm, cerebrovascular events (\<3 months), and dissection disease * Spontaneous or gaze evoked nystagmus.

Design outcomes

Primary

Measure	Time frame	Description
Treatment success after first treatment	2 year	Number of subjects achieving resolution of vertigo and nystagmus after one treatment
Number of treatments	2 year	Number of treatment necessary to achieve resolution of vertigo and nystagmus

Secondary

Measure	Time frame	Description
Dizziness Handicap Inventory (DHI) Questionnaire	2 year	Comparison of pre-treatment score and post-treatment score
Adverse events	2 year	Registration of adverse events
Recurrence rate	2 year	Recurrence of BPPV 3 and 6 months after successful treatment.

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026