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A Study of the Intervention Effect of a Hybrid Exercise Program on Frail Elderly

Hybrid Exercise Program is Frail Elderly Need: Effectiveness on the Physical Abilities and Clinical Assistance From White Box Modeling

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05832853
Enrollment
181
Registered
2023-04-27
Start date
2018-05-20
Completion date
2019-01-30
Last updated
2023-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frail Elderly Syndrome

Keywords

frailty, exercise intervention

Brief summary

The declining physical condition of frail elderly is becoming an ugent problem. Although the exercise intensity of Wu Qin Xi appears to be low, it is highly effective in the older individuals. Inspired by the characteristics and functions of Wu Qin Xi, we designed a brand new exercise intervention training program among frail older people, which incorporates Wu Qin Xi, strength exercises and endurance exercises to improve physical fitness, and even reverse the condition of frailty. Furthermore, to improve utility in clinical practice, we innovatively employed machine learning simulations to infer the condition of older adults and predict their level of frailty after the intervention.

Interventions

BEHAVIORALWu Qin Xi exercise

The training schedule for Wu Qin Xi consisted of two phases: the first phase lasted for eight weeks, while the second phase lasted for 16 weeks. In the first phase, Wu Qin Xi group was given twice repetitions of the intervention. The second phase consisted of three repetitions of the Wu Qin Xi group. Participants warmed up for 20 min prior to the intervention and cooled down for 10 min at the end.

BEHAVIORALWu Qin Xi, resistance training and endurance training

During the first 8 weeks, the training consists of learning and consolidating the movements of the Wu Qin Xi. In the second 16 weeks, participants perform a full set of movement exercises. Each resistance training session contained two lower-body exercises (seated calf raises and hip abduction) and three upper-body exercises (lateral pull downs, biceps curls, and triceps push downs) and two sets for each exercise. Endurance training is performed by continuous walking on an undisturbed indoor track for 15 min. Participants warmed up for 20 min prior to the intervention and cooled down for 10 min at the end.

BEHAVIORALResistance training and endurance training

Each resistance training session contained two lower-body exercises (seated calf raises and hip abduction) and three upper-body exercises (lateral pull downs, biceps curls, and triceps push downs) and three sets for each exercise. Endurance training is performed by continuous walking on an undisturbed indoor track for 30 min. Participants warmed up for 20 min prior to the intervention and cooled down for 10 min at the end.

Sponsors

Guang Yang, Prof. Dr.
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
60 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

1. a Fried frailty phenotype score of 3-5 points; 2. could walk for at least 6 min without support; 3. had not been able to walk in the past year other training.

Exclusion criteria

1. people who have a past mental illness or serious psychological issues which make it difficult to obey orders; 2. people who have had neurological disorders within the last six months; 3. people who must regularly participate in other training programs during the study period; 4. people who struggle to walk normally due to significant muscle and skeletal injuries and continuous joint discomfort.

Design outcomes

Primary

MeasureTime frameDescription
Assessing the endurance of frail older adults using the six-minute walk testMonth 6Assessment of endurance in frail older adults before and after intervention using the six-minute walk test
Assessing the speed of frail older adults using the ten-meter maximum walk speedMonth 6Assessment of speed in frail older adults before and after intervention using ten-meter maximum walk speed.
Using handgrip strength tests to assess strength in frail older adults.Month 6Using handgrip strength tests to assess strength in frail older adults before and after intervention
Assessment of balance in frail older adults using Time Up and Go Test.Month 6Assessment of balance in frail older adults before and after intervention using Time Up and Go Test.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026