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Evaluation of Dental Maturation and Mandibular Bone Morphology in Childhood Rheumatic Diseases

Evaluation of Dental Maturation and Mandibular Bone Morphology in Childhood Rheumatic Diseases

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05832359
Enrollment
278
Registered
2023-04-27
Start date
2023-05-19
Completion date
2023-12-05
Last updated
2023-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Childhood Rheumatic Diseases

Keywords

Childhood rheumatic diseases

Brief summary

The aim of our study is to examine possible disease-related changes in dental age and mandibular bone morphology in childhood rheumatic diseases.

Detailed description

to reveal the changes that can occur in different childhood rheumatic diseases, the treatment process of the disease and the drugs used on the dental age and mandible

Interventions

RADIATIONPanoramic rad.

In the study, digital panoramic x-rays of the patients will be evaluated and dental age estimation with Willems method and mandibular bone morphometric measurements will be made.

Sponsors

Marmara University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
6 Years to 14 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients aged 6 to 14 years with childhood rheumatism * Patients without bilateral congenital germ deficiency in the lower teeth * Patients with seven teeth (except no #8) on the left of the mandibula (No seven teeth on the left of the mandibula, there should be a symmetrical tooth on the right of the mandibula.

Exclusion criteria

* Patients with bilateral congenital germ deficiency in lower teeth in intraoral and/or radiographic examinations * Patients with asymmetry and magnification errors and where anatomical structures cannot be seen clearly in the panoramic x-ray * Patients with a significant number of missing teeth due to trauma or disease, root canal treatment, and pathological tooth structure * Patients with a history of other chronic diseases

Design outcomes

Primary

MeasureTime frameDescription
Dental Age Estimation3 monthsThe study group will be comprised of newly diagnosed pediatric patients who applied to Umraniye Training and Research Hospital Division of Pediatric Rheumatology and whose treatment is ongoing, and the control group will be composed of pediatric patients without systemic disease who applied to Marmara University Faculty of Dentistry Department of Pedodontics. In the study, digital panoramic x-rays of the patients will be evaluated and dental age estimation with Willems method will be made.

Secondary

MeasureTime frameDescription
Mandibular bone morphometric measurements3 monthsThe study group will be comprised of newly diagnosed pediatric patients who applied to Umraniye Training and Research Hospital Division of Pediatric Rheumatology and whose treatment is ongoing, and the control group will be composed of pediatric patients without systemic disease who applied to Marmara University Faculty of Dentistry Department of Pedodontics.For mandibular bone morphometric measurements, fractal analysis, that is a mathematical method describing and analyzing complex shapes and structural patterns such as the bone tissue, will be used in order to assess the bone density, using Image J software. A region of interest will be selected from panoramic radiographs. Image processing will be applied to correct for lightning irregularity, and box-counting method will be used to calculate a fractal dimension.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026