Cognitive Impairment, Schizophrenia
Conditions
Brief summary
Establish a novel vocational training program and test its validity in a pilot study.
Detailed description
40 schizophrenia patients will be recruited to join the virtual reality based vocational training program, the training effect will be compared by interview skills and problem solving before and after the training.
Interventions
BEHAVIORALVR-assisted occupational training
VR-assisted occupational training
Sponsors
National Taiwan University Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Having a diagnosis of schizophrenia based on the Diagnostic and Statistical Manual of Mental Disorders -5th version * Aged between 20 and 55 years. * Motivated to have a job. * Having a full-scale IQ \> 70 on the Wechsler Adult Intelligence Scale-version IV. * Having a PANSS positive scale \< 70, indicating a stable condition during the illness course.
Exclusion criteria
* Comorbid with other major psychiatric disorders (i.e., bipolar disorders) or neurological diseases. * Substance abuse within one year. * Visual impairment and/or hearing impairment that would preclude participation in the VR-based training program.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical ratings of schizophrenia symptoms | 8 weeks | The Positive and Negative Syndrome Scale (PANSS) is a 30-item rating scale completed by trained research staff. Scores for positive, negative, cognitive disorganization, emotional discomfort, and hostility/excitement symptoms were derived from factor-derived scoring published. \* There are 30 different symptoms rated from 1 to 7 (total score of 210). Higher the score, worse the symptoms |
| vocational skills | 8 weeks | Job interview role-play performance will be scored across nine domains: conveying oneself as a hard worker, sounding easy to work with, conveying that one behaves professionally, negotiation skills (requesting one day off), sharing things in a positive way, sounding honest, sounding interested in the position, comfort level, and establishing rapport |
| global improvement | 8 weeks | Clinical Global Impression Improvement scale (CGI-I) rating scales are commonly used measures of symptom severity, treatment response and the efficacy in treatment studies of patients with mental disorders. It is a 7-point scale that require clinician to assess how much the patient's illness has improved or worsened relative to baseline. "1" meaning very much improved, "7" meaning very much worsen. |
Countries
Taiwan
Contacts
CONTACTYi Ling Chien
PRINCIPAL_INVESTIGATORYi Ling Chien
National Taiwan University Hospital
Outcome results
None listed