Dentin Bridge
Conditions
Brief summary
Assess the clinical, radiographic, and tomographic outcomes of apexogenesis with human treated dentin matrix in young permanent molars compared to MTA.
Detailed description
The study was conducted as a split-mouth randomized clinical trial, approved by research ethics committee, Faculty of Dentistry, Tanta University, and carried out at Pediatric Dentistry Department, Faculty of Dentistry, Tanta University. The material preparation was conducted at Pharmaceutical Technology Department, Faculty of Pharmacy, Tanta University. 20 children of both sexes aged from 6 to 8 years old were selected with bilateral deeply carious young permanent mandibular first molars that are indicated for vital pulp therapy.The selected deeply carious molars were randomly divided into two groups as follows: Group I (Study group): 20 molars were treated with human TDM. Group II: (Control group): 20 molars were treated with White MTA. The participating cases were evaluated clinically and radiographically after 6, 12 and 18 months. Tomographic evaluation was performed immediate postoperatively and at 18 months.
Interventions
human treated dentin matrix is compared with mineral trioxide aggregate in apexogenesis
DRUGMineral Trioxide Aggregate
mineral trioxide aggregate was used as control
Sponsors
nora mostafa mohammed abo shanady
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
6 Years to 8 Years
Healthy volunteers
Yes
Inclusion criteria
1. Bilateral immature permanent mandibular first molars with deep carious lesions. 2. Positive response to pulp testing. 3. Normal radiographic appearance. 4. Healthy children without any systemic disease that interferes with pulp healing. 5. Patient and parent cooperation.
Exclusion criteria
1. Clinical signs and symptoms of irreversible pulpitis as spontaneous throbbing pain, tenderness to percussion, abnormal tooth mobility, swelling, or sinus tract. 2. Presence of periapical lesion, external or internal root resorption. 3. Carious furcation involvement. 4. Dystrophic calcification of the pulp. 5. Non restorable tooth.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical outcome | 18 months | patient reported pain or tenderness on palpation or percussion |
| radiographic outcomes | 18 months | radicular changes assessed by clinician from digital periapical radiograph |
| tomographic evaluation | 18 months | evidence of continuity of root development measured from cone beam computed tomography |
Countries
Egypt
Outcome results
None listed