Alcohol Drinking
Conditions
Brief summary
In this study the investigator will assess the effect of a moderate dose of alcohol on emotional responses and feelings of connection during a dyadic semi-structured social interaction
Detailed description
The study will use a within-subject crossover design with four sessions, in which participants receive alcohol or placebo across sessions. During the four sessions, the participants will engage in a conversation with a stranger, and emotional responses and feelings of connection will be assessed.
Interventions
DRUGAlcohol
Alcohol (0.8g/kg)
DRUGPlacebo
Placebo
Sponsors
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
University of Chicago
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
21 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* non-problem alcohol consumption of 2-20 drinks per week * high school diploma or equivalent * BMI between 19 and 26 * verbal fluency in English
Exclusion criteria
* High blood pressure * Any medical condition requiring regular medication * Individuals with a current (within the last year) DSM-IV Axis 1 diagnosis * Women who are pregnant or trying to become pregnant.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| facial emotional responses | during the length of the conversation (45 min) | alterations in the rate of positive facial expressions during the conversation, measured by muscle action units. These will be compared between the drug and placebo sessions |
| self-reported feelings of connection | at the end of each session (3.5 hrs post-drug administration). Changes across sessions will be assessed | self-other overlap measure ratings 1-7, greater ratings indicates greater feelings of connection |
Countries
United States
Outcome results
None listed