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Arm Swing During Walking in Early Multiple Sclerosis

Arm Swing During Walking in Early Multiple Sclerosis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05821257
Enrollment
28
Registered
2023-04-20
Start date
2021-12-01
Completion date
2023-06-30
Last updated
2023-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis, Upper Extremity Problem, Gait Disorders, Neurologic

Keywords

arm swing, multiple sclerosis, gait, foot pressure analysis

Brief summary

Multiple sclerosis (MS) is the most common central nervous system inflammatory demyelinating disease which causes motor and sensory deficits, cerebellar symptoms, and balance problems. Due to these symptoms, gait abnormalities are common in MS, even in patients with low degrees of impairment. The upper limb has an important role on postural control and gait stability. Affected arm swing movement and asymmetry during gait are common in neurological disorders such as Parkinson's disease (PD) even in early stages of the disease and arm swing treatment has been acknowledged to enhance gait and normalize arm swing in individuals with PD. The presence of arm swing changes during walking in MS patients, similar to PD, especially in the early period, may be an indicator of balance problems, this was, however, not investigated as such. Therefore, the aim of the current study is to assess the arm swing during gait in people with MS shortly after their diagnosis in early MS.

Interventions

OTHEREvaluation of the arm swing during gait

Evaluation of the arm swing during gait: The difference between the maximum flexion and extension of the shoulder is the arm swing amplitude during walking. The arm swing amplitude will be evaluated 2-dimensionally with the help of the Kinovea video player.

To understand the changes in functional mobility, Two Minute Walk Test (2MWT), Timed Up and Go (TUG) and Timed 25Foot Walk Test (T25FW) were conducted.

Sponsors

Istanbul University - Cerrahpasa
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients who were diagnosed with MS in the last 30 days, * Patients who were recovered from their symptoms and were clinically stable

Exclusion criteria

* Patients who had an acute medical illness in the past 6 months, any other neurological and psychiatric diseases * Patients who had any orthopedic, rheumatologic, or vestibular conditions that affect walking * Patients who had exacerbations between the first and second evaluations

Design outcomes

Primary

MeasureTime frameDescription
Arm swing amplitude-shoulder degrees in flexion-extension direction3 months after the baselineThe difference between the maximum flexion and extension of the shoulder will be calculated with Kinovea video player.
Arm swing amplitude-elbow degrees in flexion-extension direction3 months after the baselineThe difference between the maximum flexion and extension of the shoulder will be calculated with Kinovea video player.
Arm swing amplitude-overall degrees in flexion-extension direction3 months after the baselineThe difference between the maximum flexion and extension of the shoulder will be calculated with Kinovea video player.
Step-speed3 months after the baselineThe stepping task required patients to walk back and forth for 2 minutes over a three meters walkway which was set up with the FreeMed foot pressure analysis system (Sensor Medica, Guidonia Montecelio). Step speed outcome was collected from foot pressure analysis system.
Two Minute Walk Test (2MWT)3 months after the baselineIt is a measure of self-paced walking ability and functional capacity. The person is encouraged to walk as fast as they can, safely, without assistance for two minutes and the distance is measured.
Timed Up and Go (TUG)3 months after the baselineTo determine fall risk and measure the progress of balance, sit to stand and walking.It uses the time that a person takes to rise from a chair, walk three meters, turn around 180 degrees, walk back to the chair, and sit down while turning 180 degrees.
Timed 25Foot Walk Test (T25FW)3 months after the baselineThe T25-FW is a quantitative mobility and leg function performance test based on a timed 25-walk.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026