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Characterization of Mentalization Profiles Related to Emotional Regulation Among Teenagers With Behavioral Disorders

Characterization of Mentalization Profiles Related to Emotional Regulation Among Teenagers With Behavioral Disorders

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05820581
Acronym
CARMEN
Enrollment
65
Registered
2023-04-19
Start date
2023-06-26
Completion date
2026-06-30
Last updated
2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adolescent Behavior Disorder, Eye Movements

Keywords

Mentalisation, Emotion regulation, Adolescents, Neurophysiological parameters

Brief summary

Behavioral disorders in adolescents are defined by a set of diverse behaviors (such as aggressiveness, agitation, clastic crisis, running away and endangerment) whose common characteristic is the predominance of action/ mentalization. These disorders are associated with significant morbidity and high mortality linked to a high rate of suicide or attempted suicide. Behavioral disorders are also associated with an alteration of mentalizing capacities, that is the psychic process by which the adolescent imagines and interprets his behavior and that of others on the basis of mental states such as needs, desires, beliefs or feelings. The disorders are also associated with emotional dysregulation. To date, the psychopathological processes underlying behavioral disorders in adolescents are unknown and prevent from offering appropriate psychological care. Thus, it seems essential to characterize this clinical population by integrating both its intrapsychic representations and the physiological parameters of emotional regulation associated with it. This project is a first step towards a larger-scale research project aimed at evaluating treatment by TBM (therapies based on mentalization) in adolescents with behavioral disorders.

Detailed description

Behavioral disorders in adolescents are defined by a set of behaviors (such as aggressiveness, agitation, clastic crisis, running away and endangerment) whose common characteristic is the predominance of action over mentalization and opposition to normal socialization processes. These disorders are associated with significant morbidity and high mortality linked to a high rate suicide or attempted suicide. Behavioral disorders in adolescence are linked to defects of mentalization (i.e. the psychic process by which the adolescent imagines and interprets his behaviors and to alterations in emotional regulation capacities. This emotional dysregulation has several components, including motor and physiological components. Moreover, this dysregulation is constructed in a dynamic process linked to the environment, including the adolescent's relationship with parents. To date, the psychopathological processes underlying behavioral disorders in the teenager are unknown, which prevents from offering appropriate psychological care. Thus, it seems essential to characterize adolescents behavior, by integrating both mentalizing capacities, the physiological parameters of their emotional regulation and the interactive patterns with their parents. This approach allow to overcome the difficulty of adolescents to use words to express what they feel and thus to understand their psychic functioning and the strategies, which they put in place to regulate their emotions. This study is a monocentric cross-sectional descriptive observational study. Objectives of this study is to describe the mentalization profiles of adolescents with mental disorders behavior and to evaluate: * Oculomotor parameters of emotional regulation * Physiological parameters of emotional regulation (Electrodermal Activity, RED) * Self-assessed mentalizing abilities (RFQ-Y scale) * Emotional regulation (DERS scale) * The emotional and behavioral functioning of adolescents (YSR scale) * Attachment characteristics of adolescents (ARSQ scale) * The interactions of the adolescent with his parent (GPACS scale) * Parental reflexive capacities (RFQ scale). This research was developed to support a comprehensive understanding of adolescent processes with the integration of bio-neuro-social parameters. The aim of this study is to establish mentalization profiles of the clinical population of adolescents with behavioral disorders and their neurophysiological correlates of emotional regulation. These first data are essential for a better understanding of this clinical population and a starting point for future research; particularly to develop therapies based on mentalization in this population and to evaluate their effectiveness.

Interventions

BEHAVIORALMentalisation

Hypomentalisation, hypermentalisation, correct mentalisation, lack of mentalisation

Sponsors

Centre Hospitalier Universitaire de Besancon
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
12 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* Teenage girls or boys aged 12 to 17 * Adolescent(s) with externalized behavioral disorder(s): running away, suicide attempts, self-aggression (scarification, self-mutilation), taking drugs, hetero-aggressive behavior, theft, conduct disorders sexual, oppositional behavior, lies, clastic anger. * Non-objection of the adolescent to participate in the study. * Written consent of the two holders of parental authority

Exclusion criteria

* Intellectually disabled * Autism Spectrum Disorder * Psychotic disorder

Design outcomes

Primary

MeasureTime frameDescription
eye fixation duration evaluated with eyes tracker12 monthsfixation duration (time in millisecond)
eye dwell time evaluated with eyes tracker12 monthsdwell time (time in millisecond)
eye fixation count evaluated with eyes tracker12 monthsfixation count ( time in millisecond)

Secondary

MeasureTime frameDescription
DERS score12 monthsDifficulties in Emotion Regulation Scale (DERS)
ARSQ score12 monthsAdolescent relationship scale questionnaire
MASC Score12 monthsMentalization score
GPACS interaction evaluation12 monthsGeneral Practitioner Attitudes and Confidence Scale is a tool to measure confidence and attitude.
parent's RFQ score12 monthsReflective Functioning Questionnaire for parents
YSR score12 monthsyouth self report score
RFQ-Y score12 monthsReflective Function Questionnaire for Youth

Countries

France

Contacts

Primary ContactLauriane Vulliez, PR
lvulliez@chu-besancon.fr(0033)0381218154
Backup ContactJulie Mathieu, MD
jmathieu@chu-besancon.fr(0033)0381218154

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026