Palate; Wound
Conditions
Brief summary
The aim of this study is to compare the effect of using 2% curcumin gel versus gelatin sponge when applied to palatal donor site in pain management and wound healing after free gingival graft harvesting.
Interventions
OTHERcurcumin gel 2%
curcumin gel 2%
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. Systematically healthy patient (American Society of Anesthesiology class I and II). 2. Male or female 3. Patients with mucogingival defects scheduled for free gingival graft. 4. Patients with good oral hygiene.
Exclusion criteria
1. Patients with any uncontrolled local or systemic disease where periodontal plastic surgery might be contraindicated. 2. History of recent periodontal surgery at the donor site. 3. Smokers. 4. Pregnancy and lactation. 5. Patients allergic to the used agents, 6. Severe gagging reflex. 7. Inability or unwillingness to provide informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| post-operative pain | one week post operative | post -operative pain measured by visual analouge scale from 0 (no pain) to 10 (highest pain value) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Soft tissue healing of the palatal wound | up to three weeks post-operative | Soft tissue healing of the palatal wound measured by Modified Landry's wound healing score from 1 indicates poorest healing to 5 indicates excellent healing |
| Re-epithelization of the palatal wound | up to three weeks post-operative | Re-epithelization of the palatal wound using H2O2 test |
Countries
Egypt
Contacts
Primary ContactTansim k ABdelrahman, BDS
Backup Contactmohamed atef, PHD
Outcome results
None listed