COPD Exacerbation, Hypoxemia, Pneumonia, Respiratory Disease
Conditions
Keywords
oxygen, oximeter
Brief summary
The oximeter is an instrument for monitoring patients receiving oxygen therapy. It displays pulse oxygen saturation (SpO2), which is a reflection of arterial oxygen saturation (SaO2). An accurate SpO2 value is essential for optimal management of the O2 flow delivered to patients. Several factors can influence this measurement and the choice of ventilatory support: the type of oximeter used, skin pigmentation and the oxygenation goal. The objective of our study is to evaluate the impact of the oxygenation goal and the oximeter used on oxygen flows in patients with COPD (or with hypercapnia, or at risk of hypercapnia) and in patients without COPD (in particular pneumonia, pulmonary fibrosis and other pathologies) Our hypothesis is that the SpO2 target and oximeter used will have an impact on oxygen flows and that these effects will be synergistic in these different populations.
Interventions
DEVICEMasimo oximeter
During this period, the Masimo oximeter Radical 7 was used for SpO2 reading
DEVICENellcor oximeter
During this period, the Nellcor oximeter N-600 was used for SpO2 reading
DEVICENonin oximeter
During this period, the Nonin oximeter was used for SpO2 reading
Sponsors
Laval University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ≥ 18 years old * On conventional oxygen therapy with SpO2 between 88 and 100% with the usual oximeter and nasal cannula. * SpO2 \< 92% in ambient air with the usual oximeter
Exclusion criteria
* No availability of the SpO2 signal with the usual oximeter * False nails or nail polish * Severe anemia documented on the last blood count during the current hospitalization (Hb \< 80g/L)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxygen flow | assessed up to 10 minutes | the mean oxygen flow to reach the SpO2 target +/- 1% during 2 minutes for each period and each oximeter |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Partial oxygen weaning | assessed up to 10 minutes - until SpO2 target stability for 2 minutes | Rate of partial oxygen weaning (Oxygen flow \<=0.5 L/min) to reach the SpO2 target for each period and each oximeter |
| Complete oxygen weaning | assessed up to 10 minutes - until SpO2 target stability for 2 minutes | Rate of complete oxygen weaning (Oxygen flow \<=0.1 L/min) to reach the SpO2 target for each period and each oximeter |
| High oxygen flow | assessed up to 10 minutes - until SpO2 target stability for 2 minutes | Rate of high oxygen flow (Oxygen flow \>5.0 L/min) to reach the SpO2 target for each period and each oximeter |
| Oximeter bias comparison | assessed up to 10 minutes - until SpO2 target stability for 2 minutes | the mean bias between the result of the different oximeter |
Countries
Canada
Outcome results
None listed