Vascular Diseases
Conditions
Brief summary
The goal of this study is to determine the effects of high-intensity interval training and crossover point exercise training on vascular health in young overweight women.
Detailed description
In recent years, improving cardiovascular health through exercise has become a popular research question, however, it is not clear which intensity and modes of exercise bring more benefits. Crossover point(COP) intensity has great medical potential as a personalized exercise intensity that is based on substrate utilization mode, especially in overweight and obese people.On the other hand, several studies have demonstrated that HIIT is an effective method in improving vascular endothelial dysfunction. During our study, we evaluated the vascular health changes in young overweight women who received either COP exercise or HIIT exercise for 10 weeks.
Interventions
BEHAVIORALhigh-intensity interval training (HIIT)
Participants in both the COP and HIIT groups underwent 30 sessions of exercise performed over 10 weeks. The training sessions in the HIIT group involved five high-intensity intervals of 4 minutes each (running or walking on a treadmill) at 85% VO2max interspersed with 3 minutes of low-intensity walking.
BEHAVIORALcrossover point(COP) exercise training
Participants in both the COP and HIIT groups underwent 30 sessions of exercise performed over 10 weeks. The COP exercise training sessions involved 45 minutes of continuous exercise at the COP on a treadmill.
Sponsors
Beijing Sport University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
1. Female, 18-30 years old 2. Body mass index (BMI) \< 28 kg/m2 and ≥ 24 kg/m2 3. No exercise habit, and no recent new exercise plan 4. No contraindications to exercise
Exclusion criteria
1. Participates had an orthopedic or other condition that limited participation in daily exercise 2. Participates had a history of myocardial infarction, stroke, diabetes mellitus, chronic respiratory disease or cancer 3. Participates had smoking or alcohol behavior
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| brachial-ankle pulse wave velocity (baPWV) | 10 weeks | The change of baPWV before and after intervention |
| blood pressure | 10 weeks | The change of blood pressure before and after intervention |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Interleukin 6 (IL-6) | 10 weeks | The change of IL-6 level before and after intervention |
| Homocysteine (HCY) | 10 weeks | The change of HCY level before and after intervention |
Countries
China
Outcome results
None listed