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The Association Between Anemia and Cardiomegaly

The Association Between Anemia (Hemoglobin Level) and Cardiomegaly Based On Chest Radiograph and Echocardiography

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05816278
Enrollment
56
Registered
2023-04-18
Start date
2023-05-01
Completion date
2023-12-20
Last updated
2026-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia in Children, Cardiomegaly

Brief summary

Anemia is one of the major global problems that continues to this day. According to World Health Organization (WHO) data, anemia is found in 1.62 billion people or equivalent to 24.8% of the world's population while, the prevalence of anemia in children under 6 years of age in Indonesia reached 38.4%. Anemia, if undiagnosed or untreated for a long period of time can lead to multiorgan failure. The cardiovascular system is the most commonly affected system in chronic anemia. Between one-third and two-thirds of patients with severe anemia have cardiomegaly and this will return to normal within a few weeks after the anemia is well managed. This abnormality can be evaluated on chest radiograph or echocardiography.

Interventions

None listed

Sponsors

Universitas Sumatera Utara
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
1 Days to 18 Years

Inclusion criteria

* Anemia patients aging maximum 18 years old * Anemia patients who had undergone chest radiograph and echocardiography

Exclusion criteria

* Anemia patients who had undergone definitive surgery * Anemia patients who had took iron supplementation in the last 3 months * Anemia patients who had other anemic conditions such as chronic kidney disease or hemolytic anemia

Design outcomes

Primary

MeasureTime frameDescription
AnemiaApril 2023 - September 2023Diagnosis of anemia based on Hb levels according to WHO classification
CardiomegalyApril 2023 - September 2023Diagnosis of cardiomegaly based on chest radiograph and echocardiography

Countries

Indonesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 25, 2026