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Effect of Ketogenic Diet on Peri-operative Complications of Right Laparoscopic Adrenalectomy in Obese Patients

Effect of Ketogenic Diet on Peri-operative Complications of Right Laparoscopic Adrenalectomy in Obese Patients

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05816031
Enrollment
80
Registered
2023-04-18
Start date
2020-01-01
Completion date
2023-12-15
Last updated
2023-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adrenalectomy; Status, Obesity, Morbid

Brief summary

Ketogenic diet is often prescribed to morbid obese patients scheduled for bariatric surgery in order to reduce liver size, thus making surgery less demanding. The study aim to investigate the possible effects of ketogenic diet on intra- and peri-operative complications of right laparoscopic adrenalectomy in obese patients; researchers will analyze intra- and peri-operative outcomes among obese patients who underwent laparoscopic right adrenalectomy, comparing the two arms with and without ketogenic diet.

Detailed description

Ketogenic diet is often prescribed to morbid obese patients scheduled for bariatric surgery in order to reduce liver size, thus making surgery less demanding. Due to a standard trans abdominal laparoscopic right adrenalectomy is performed with the patient in left lateral position, it is necessary to retract liver in order to expose the right adrenal gland and the cava vein. It is therefore evident how a reduced size liver may allow a faster, easier and safer surgery. Finding a normal size liver is uncommon in patients presenting with a body mass index above 30 Kg/m2. According to this, patients scheduled to right laparoscopic adrenalectomy and belonging to the case arm, will be administered a standard 21 days ketogenic diet before surgery. Conversely this will not be prescribed to patients belonging to control group. Ketogenic diet is based on a standard diet plus a ketogenic product to be taken once daily for 21 days. In both groups patients will undergo abdominal ultrasound before surgery.

Interventions

DIETARY_SUPPLEMENTKetogenic diet

Ketogenic diet administrated to obese patients planned for right laparoscopic adrenalectomy

Sponsors

Federico II University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* BMI \> 30 Kg/m2 * Planned for laparoscopic right adrenalectomy * Age \> 18y.o. * No contraindications for ketogenic diet

Exclusion criteria

* Diabetes * Patients requiring conversion to open surgery * BMI \< 30 Kg/m2 * Age \< 18 y.o.

Design outcomes

Primary

MeasureTime frameDescription
Peri-operative complicationsComplications occurring during surgery and within 30 days from surgeryPre and post-operative (within 30 days) complications of laparoscopic adrenalectomy

Countries

Italy

Contacts

Primary ContactMario Musella
mario.musella@unina.it00390817462880

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026