Gynecologic Cancer
Conditions
Brief summary
The aim of this prospective observational diagnostic study is to investigate the diagnostic accuracy od extrapelvic disease detection using Whole-body-MRI (WB-MRI) in patients with gynecologic cancer candidate to the pelvic exenteration.
Interventions
None listed
Sponsors
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \> 18 years * Written Informed Consent * All patients with recurrent gynecological cancer that are planned to undergo pelvic exenteration or laterally extended pelvic resection, both with curative and palliative intent * Patients considered fit for srugery
Exclusion criteria
* Controindication to MRI (Claustrophobia, implanted ferromagnetic materials or foreign objects, Known intolerance or controindication to the MRI contrast agent, cardiac pacemaker) * Individuals who are not able or willing to tolerate the required prologed stationary supine position during examination (approximately 40-60 minutes) * Patient unable to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of diagnostic accuracy for extrapelvic disease detection using whole-body MRI | Through study completion, an average of 2 yearS |
Secondary
| Measure | Time frame |
|---|---|
| Agreement between WB-MRI and PET-CT in detecting extrapelvic involvement | Through study completion, an average of 2 yearS |
Countries
Italy
Outcome results
None listed