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Non Contrast CT in Acute Appendicitis

Diagnostic Accuracy of Non-Contrast Computed Tomography in Correlation With Ultrasound in Detecting Acute Appendicitis in Adults

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05815446
Enrollment
78
Registered
2023-04-18
Start date
2023-04-20
Completion date
2023-12-30
Last updated
2023-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Appendicitis

Brief summary

To evaluate Diagnostic accuracy of Non-contrast CT in correlation with ultrasound in diagnosis of acute appendicitis in adults

Detailed description

Acute appendicitis is a prevalent cause of abdominal pain, with an estimated lifetime risk of 7 to 9%.\[1\] Diagnosing appendicitis on CT has a sensitivity and specificity of 87% and 76%, respectively. Classically, diagnosis of acute appendicitis is by identifying an enlarged appendix (greater than 6 mm in diameter) . Some studies suggest using a cut-off value of over 7 mm to improve the prognostic capability of CT. On the other hand, appendicitis is regularly diagnosed using radiology studies. In fact, imaging is often the deciding factor between operative and non-operative management. Though the diagnosis can be clinical following a thorough history and physical, imaging is regularly employed to confirm the diagnosis in question. The most commonly used radiographic study is the CT scan, given its speed, sensitivity, and specificity. US is also relatively useful modality to diagnose acute appendicitis, it has its limitations. Ultrasound is highly operator dependent and tends to work best on individuals with less fat and muscle content in their abdomen (i.e., children). Currently, the negative appendectomy is less than 12% in men but can be up to 33% in women; accurate imaging studies could reduce the number of unnecessary surgeries performed on patients. It is, therefore, essential to know which study will provide the clinician with the most accurate information for their specific clinical scenario.

Interventions

DEVICECT

NON CONTASR COMPUTED TOMOGRAPHY

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years

Inclusion criteria

* Adult patient (male or female) with clinical suspicion of acute appendicitis .

Exclusion criteria

* pregnant ladies and patients with history of appendectomy

Design outcomes

Primary

MeasureTime frameDescription
accuracy of non contrast CT in correlation with ultrasound in acute appendicitis .baselineDiagnostic Accuracy of Non-Contrast Computed Tomography in Correlation with Ultrasound in Detecting Acute Appendicitis in Adults.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026